Results 61 to 70 of about 35,403 (120)

PGC-1α expression in murine AgRP neurons regulates food intake and energy balance

Molecular Metabolism, 2016
Objective: Food intake and whole-body energy homeostasis are controlled by agouti-related protein (AgRP) and pro-opiomelanocortin (POMC) neurons located in the arcuate nucleus of the hypothalamus.
Jonathan F. Gill, Julien Delezie, Gesa Santos, Christoph Handschin   +3 more
doaj   +1 more source

PGC-1α participates in regulating mitochondrial function in aged sarcopenia through effects on the Sestrin2-mediated mTORC1 pathway

Experimental Gerontology
Background: Mitochondrial dysregulation in skeletal myocytes is considered a major factor in aged sarcopenia. In this study, we aimed to study the effects of peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) on Sestrin2 ...
Yimin Fu, Lei Tao, Xiaojun Wang, Binyou Wang, Weilin Qin, Lei Song   +5 more
doaj   +1 more source

PGC-1α and PPARs cooperatively mediate photoreceptor neuroprotection in rd1 mouse inherited retinal degeneration. [PDF]

Cell Death Dis
Wang L, Yan J, Sancho-Pelluz J, Yang Q, Hu Z, Jiao K, Seeliger MW, Paquet-Durand F.   +7 more
europepmc   +1 more source

Effect of Porphyromonas gingivalis Infection on PGC-1α in Skeletal Muscle After Endurance Training In Vivo. [PDF]

Clin Exp Dent Res
Hayashi K, Takeuchi Y, Kobayashi H, Tanabe G, Churei H, Ueno T, Fueki K.   +6 more
europepmc   +1 more source

Exercise alleviates age-related osteoarthritis associated with PGC-1α activation to suppress chondrocyte senescence and aberrant glycolysis. [PDF]

J Orthop Translat
Cao Y, Lao A, Zhu S, Jin F, Sha Z, Zhuang Y, Zhan H, Wang L, Li H, Lin K, Zhu R.   +10 more
europepmc   +1 more source

S100A9 Aggravates Cardiac Fibrosis by TLR4/PGC-1α Mediated Macrophage-Myofibroblast Crosstalk. [PDF]

J Extracell Vesicles
Zhao Y, Zhang Y, Yuan Q, Fang X, Sheng J, Deng Y, Shen S.   +6 more
europepmc   +1 more source

PGC-1α pathway dysregulation disrupts myofiber specification in a mouse model of SBMA. [PDF]

JCI Insight
Kuo CJ, Chopp LB, Yu Z, Ni L, Zhao HT, Lim J, Lieberman AP.   +6 more
europepmc   +1 more source

AMPK/ SIRT1 signaling pathway activation acts on PGC-1α/ PPARγ to alleviate sepsis-acquired weakness. [PDF]

Cell Death Discov
Li L, Shi L, Liu M, Fang Q.
europepmc   +1 more source

Molecular regulation of PGC-1α: from protein-protein interactions and post-translational modifications to pharmacological modulation. [PDF]

J Mol Med (Berl)
Rios WQ, Silva CM, Ferreira R, Gomes JRB.   +3 more
europepmc   +1 more source

Correction: RIPC improves myocardial injury by promoting mitochondrial protection via the PGC-1α/Nrf2 pathway. [PDF]

J Biol Chem
Zhao Z, Zhang Z, Li X, Ding J, Li M.
europepmc   +1 more source