Results 81 to 90 of about 17,993 (204)

The role of prostaglandin E₂ (PGE ₂) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia

BMC Gastroenterology, 2010
Background We have previously found that TLR4-deficient (TLR4-/-) mice demonstrate decreased expression of mucosal PGE 2 and are protected against colitis-associated neoplasia.
Hayes Lory A, Ungaro Ryan, Hsu David, Xu Ruliang, Chen Anli, Conduah Daisy, Breglio Keith, Sotolongo John, Hernandez Yasmin, Pastorini Cristhine, Abreu Maria T, Fukata Masayuki   +11 more
doaj   +1 more source

Reveses democráticos en América Latina

Interconectando Saberes
Este estudio tiene como objetivo analizar el fenómeno de la degradación democrática en América Latina, centrándose en los casos de Venezuela, Nicaragua y El Salvador.
Rodolfo Silva Marques, André Silva de Oliveira   +1 more
doaj   +1 more source

Metabolic Syndrome as a Determinant of Bidirectional Transitions Between Frailty States: Evidence From the Whitehall II Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Understanding interactions between geriatric syndromes is central for promoting healthy aging. Frailty is among the most relevant, as it predicts disability, falls, hospitalization and mortality. In addition, emerging evidence also indicates that metabolic factors play a key role in the frailty development.
Steve Kevin Njouonkep Sime, Bi Boli Anselme Stéphane Irié, Etienne Jules, Léopold Fezeu K., Estelle Pujos‐Guillot, Blandine Comte   +5 more
wiley   +1 more source

Fire‐induced shifts in activity patterns of predators and prey in the Brazilian Pantanal

The Journal of Wildlife Management, Volume 90, Issue 6, August 2026.
Using camera trap data, we observed that 5 of 6 prey species showed statistically significant changes in temporal activity patterns, while jaguars were the only predator species to adjust activity when comparing pre‐fire and post‐fire periods in an isolated rocky formation in the Pantanal region.
Sergio Eduardo Barreto de Aguiar, Grasiela Edith Oliveira de Porfirio, Leonardo França do Nascimento, Josiel de Oliveira Coelho, Mariana Alves Carvalho Queiroz, Geovani Vinco Tonolli, Wener Hugo Arruda Moreno, Diego Francis Passos Viana, Rocío Bardales, Matthew Hyde, Ricardo Daniel Ortiz‐Hoyos, Nayara Yoshie Sano, Filipe Martins Santos   +12 more
wiley   +1 more source

Natural Resources and Political Patronage in Africa: An Ethnicity Level Analysis

Review of Development Economics, Volume 30, Issue 3, Page 1957-1972, August 2026.
ABSTRACT We investigate the effect of resource discoveries on ethnicity‐level political patronage in Africa using a large geospatial dataset of 254 ethnic groups in 15 countries over the period 1960–2004. We find that the first (or single first) resource discovery in a virgin ethnic homeland increases the share of cabinet posts of that ethnicity.
Sambit Bhattacharyya, Nemera Mamo
wiley   +1 more source

Developmental Trajectories and Sequential Analysis of Triadic Joint Attention

Scandinavian Journal of Psychology, Volume 67, Issue 4, Page 1142-1156, August 2026.
ABSTRACT Triadic joint attention (JA) refers to the shared focus of a child and an interlocutor on an object or event, accompanied by mutual awareness of this shared attention. Although JA is associated with early social interaction and later language development, its definitions and behavioral markers vary across studies and are often restricted to ...
Tove Nilsson Gerholm, Petter Kallioinen, Tatjana von Rosen   +2 more
wiley   +1 more source

Unique/Rapid Feedback Mechanisms of PGD2 and PGE2 as Local/Short‐Lived Autacoids; Implications of Biased Activities by Their Metabolites

BioEssays, Volume 48, Issue 7, July 2026.
Since autacoids are short‐lived bioactive substances that act near their site of biosynthesis, the biased activities of prostanoid metabolites may have significant physiological implications with regard to the newly defined and/or re‐acknowledged as unique and novel nongenomic feedback mechanisms, which may be one of very important roles of prostanoids
Hiromichi Fujino, Keijo Fukushima
wiley   +1 more source

Chemical Characterization and In Vivo Safety Assessment of Aqueous Extract From Anacardium occidentale L. (Anacardiaceae) Leaves

Chemistry &Biodiversity, Volume 23, Issue 7, July 2026.
Anacardium occidentale leaf aqueous extract showed rich polyphenolic composition, including flavonoids, tannins, and phenolic acids. Acute toxicity in mice revealed no mortality or adverse effects, with LD50 >2000 mg/kg and GHS Class 5. Genotoxicity assays were negative, supporting safety and potential phytopharmaceutical development, pending chronic ...
Elinado Francisco de Lima Bento, Caio Everton Nunes da Silva, Talita Giselly dos Santos Souza, Camylla Janiele Lucas Tenório, Natanael Teles Ramos de Lima, Cristiano Aparecido Chagas, José Maria Barbosa Filho, Magda Rhayanny Assunção Ferreira, Luiz Alberto Lira Soares, Samuel Paulo Cibulski, Alisson Macário de Oliveira, Thiago Henrique Napoleão   +11 more
wiley   +1 more source

Urinary prostaglandin metabolites evaluation for activity monitoring in inflammatory bowel disease

Scientific Reports
Inflammatory bowel diseases cause chronic intestinal inflammation, including Crohn’s disease (CD) and ulcerative colitis (UC). Prostaglandin E-major urinary metabolite (PGE-MUM) is a urine biomarker for disease activity in IBD.
Renata d’Inca, Hana Manceau, Lucia Zanni, Laura Vernoux, Xavier Treton, Katell Peoc’h   +5 more
doaj   +1 more source

癫痫患儿血清同型半胱氨酸、S100B蛋白、NPY水平与预后的相关性分析

Zhongguo shiyan zhenduanxue, 2020
癫痫（PGE）是一种由大脑某些神经元兴奋性过高引起异常放电导致脑部功能异常的神经系统疾病,具有发病率高、发作时间短,发作时神经功能紊乱以及难控制易反复发作的特点[1,2]。儿童PGE是PGE患者的主要组成部分,约占总PGE患者的70%-80%,严重影响儿童的社会生活。PGE发病机制较为复杂,但经研究表明,中枢神经损失与炎症反应在PGE反复发作过程中起重要作用[3]。本研究旨在探讨PGE患儿血清同型半胱氨酸（Cys）、
李学广, 苏志恒, 梁其跃, 高成思   +3 more
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