Results 1 to 10 of about 4,872 (106)

Utility of a rapid assay for prostaglandin E-major urinary metabolite as a biomarker in pediatric ulcerative colitis [PDF]

Scientific Reports, 2023
Prostaglandin E-major urinary metabolite (PGE-MUM) is a urinary biomarker reflecting ulcerative colitis (UC) activity. This prospective observational study aimed to evaluate the usefulness of PGE-MUM via rapid chemiluminescent enzyme immunoassay in ...
Shin-ichiro Hagiwara, Naoki Abe, Kenji Hosoi, Tomoko Hara, Takashi Ishige, Hirotaka Shimizu, Tatsuki Mizuochi, Toshihiko Kakiuchi, Reiko Kunisaki, Ryo Matsuoka, Hiroki Kondou, Fumihiko Kakuta, Yoshiko Nakayama, Takeshi Kimura, Takatoshi Maeyama, Hitoshi Honma, Daishi Hirano, Masayuki Saruta, Tsutomu Yoshida, Isao Okayasu, Yuri Etani   +20 more
doaj   +4 more sources

Prostaglandin E-major urinary metabolite versus fecal immunochemical occult blood test as a biomarker for patient with ulcerative colitis [PDF]

BMC Gastroenterology, 2020
Background Prostaglandin E-major urinary metabolite (PGE-MUM) may be a novel biomarker for evaluating disease activity in ulcerative colitis (UC). We compared its usefulness to that of the fecal immunochemical occult blood test (FIT). Methods PGE-MUM and
Natsuki Ishida, Takahiro Miyazu, Ryosuke Takano, Satoshi Tamura, Shinya Tani, Takuma Kagami, Mihoko Yamade, Yasushi Hamaya, Moriya Iwaizumi, Satoshi Osawa, Takahisa Furuta, Hiroaki Miyajima, Ken Sugimoto   +12 more
doaj   +5 more sources

Comparison between Prostaglandin E-major urinary metabolite and C-reactive protein levels to reflect endoscopic scores in patients with ulcerative colitis [PDF]

Scientific Reports, 2021
Prostaglandin E-major urinary metabolite (PGE-MUM) and C-reactive protein (CRP) are useful biomarkers in patients with ulcerative colitis. However, whether changes in endoscopic scores over time are reflected in the values of these biomarkers has not ...
Natsuki Ishida, Satoshi Tamura, Takahiro Miyazu, Shinya Tani, Mihoko Yamade, Moriya Iwaizumi, Yasushi Hamaya, Satoshi Osawa, Takahisa Furuta, Ken Sugimoto   +9 more
doaj   +5 more sources

Significant increase in prostaglandin E-major urinary metabolite with physical exercise suggesting muscle inflammation

All Life, 2023
Introduction: Prostaglandin E-major urinary metabolite (PGE-MUM) may be a good biomarker of inflammation and useful in monitoring diseases, without the necessity of invasive sampling. To see whether inflammation in muscles occurs during physical exercise,
Isao Okayasu, Hatsumi Kuroiwa, Kanako Shinkawa, Kaori Hayashi, Seiichi Sato, Noboru Iwata, Goichi Tano, Ryo Sekizaki, Kazuyuki Umeda, Hiromitsu Ohnishi   +9 more
doaj   +3 more sources

Prostaglandin E-major urinary metabolite as a potential biomarker of muscle inflammation following physical exercise, considering gender differences [PDF]

Scientific Reports
Prostaglandin E-major urinary metabolite (PGE-MUM) may be a useful biomarker for assessing muscle inflammation caused by physical exercise. To explore this, both male and female volunteer university students (n = 18) performed gradual loading treadmill ...
Isao Okayasu, Jiapeng Huang, Zenya Fujita, Amanda J. Cox, Katsuhiko Suzuki   +4 more
doaj   +3 more sources

Simultaneous analyses of urinary eicosanoids and related mediators identified tetranor-prostaglandin E metabolite as a novel biomarker of diabetic nephropathy

Journal of Lipid Research, 2021
Diabetic nephropathy is a major complication of diabetes mellitus, and thus novel biomarkers are desired to evaluate the presence and progression of diabetic nephropathy.
Yoshifumi Morita, Makoto Kurano, Eri Sakai, Motoji Sawabe, Junken Aoki, Yutaka Yatomi   +5 more
doaj   +3 more sources

Clinical Determinants and Bone Metabolic Correlates of 24-h Urinary PGE2 and PGEM Excretion in Chinese Adults: A Multicenter Cross-Sectional Study [PDF]

Biomedicines
Background: Prostaglandin E2 (PGE2) is a key lipid mediator involved in inflammation and bone homeostasis. Its systemic production is reliably reflected by 24 h urinary excretion of PGE2 (U-PGE2) and its major metabolite (U-PGEM).
Qi Lu, Li Shen, Yang Xu, Zhenlin Zhang
doaj   +2 more sources

Optimal positioning of biomarkers according to ulcerative colitis activity [PDF]

Scientific Reports
The diagnostic performance and clinical utility of fecal calprotectin (FC), fecal immunochemical occult blood test (FIT), leucine-rich alpha-2 glycoprotein (LRG), C-reactive protein (CRP), and prostaglandin E-major urinary metabolite (PGE-MUM) as ...
Natsuki Ishida, Tomohiro Takebe, Kenichi Takahashi, Yusuke Asai, Tomoharu Matsuura, Mihoko Yamade, Moriya Iwaizumi, Yasushi Hamaya, Takanori Yamada, Satoshi Osawa, Ken Sugimoto   +10 more
doaj   +2 more sources

Effect of Dysglycemia on Urinary Lipid Mediator Profiles in Persons With Pulmonary Tuberculosis

Frontiers in Immunology, 2022
BackgroundOxidized lipid mediators such as eicosanoids play a central role in the inflammatory response associated with tuberculosis (TB) pathogenesis. Diabetes mellitus (DM) leads to marked changes in lipid mediators in persons with TB.
María B. Arriaga, María B. Arriaga, María B. Arriaga, María B. Arriaga, Farina Karim, Artur T.L. Queiroz, Artur T.L. Queiroz, Mariana Araújo-Pereira, Mariana Araújo-Pereira, Mariana Araújo-Pereira, Beatriz Barreto-Duarte, Beatriz Barreto-Duarte, Beatriz Barreto-Duarte, Caio Sales, Caio Sales, Mahomed-Yunus S. Moosa, Matilda Mazibuko, Ginger L. Milne, Fernanda Maruri, Carlos Henrique Serezani, John R. Koethe, Marina C. Figueiredo, Afrânio L. Kritski, Marcelo Cordeiro-Santos, Marcelo Cordeiro-Santos, Marcelo Cordeiro-Santos, Valeria C. Rolla, Timothy R. Sterling, Alasdair Leslie, Alasdair Leslie, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, the RePORT Brazil and South Africa consortia, Alice M. S. Andrade, Michael S. Rocha, Vanessa Nascimento, Juan M. Cubillos-Angulo, Hayna Malta-Santos, Jéssica Rebouças-Silva, Sayonara M. Viana, Saulo R. N. Santos, André Ramos, Alysson G. Costa, Jaquelane Silva, Jamile G. de Oliveira, Secretaria, Aline Benjamin, Adriano Gomes-Silva, Flavia M. Sant’Anna, Francine P. Ignácio, Maria Cristina Lourenço, Elisangela C. Silva, Adriana S. R. Moreira, Mayla Mello   +56 more
doaj   +1 more source

Role of Biomarkers in the Diagnosis and Treatment of Inflammatory Bowel Disease

Life, 2021
The number of patients with inflammatory bowel disease (IBD) is increasing worldwide. Endoscopy is the gold standard to assess the condition of IBD. The problem with this procedure is that the burden and cost on the patient are high.
Kohei Wagatsuma, Yoshihiro Yokoyama, Hiroshi Nakase   +2 more
doaj   +1 more source