Results 121 to 130 of about 122,171 (336)

PGE2 suppression of innate immunity during mucosal bacterial infection

Frontiers in Cellular and Infection Microbiology, 2013
Prostaglandin E2 (PGE2) is an important lipid mediator in inflammatory and immune responses during acute and chronic infections. Upon stimulation by various proinflammatory stimuli such as lipopolysaccharide (LPS), interleukin (IL)-1β, and tumor ...
Mallory eAgard, Saja eAsakrah, Lisa A Morici   +2 more
doaj   +1 more source

Berries: Health Effects via Modulation of the Gut Microbiota

Food Frontiers, EarlyView.
ABSTRACT Berries are widely regarded as beneficial foods, rich in polyphenols, flavonoids, and other bioactive compounds that could positively influence human health. Although the gut microbiota plays a crucial role in metabolism and physiology of humans, the interaction between berries and human gut microbiota activity remains unclear.
Manjin Xu, Yunfeng Xu, Lizhi Wu, Huixia Niu, Bei Gao, Kai Sun, Xueqing Li, Mingluan Xing, Zhe Mo, Zhijian Chen, Pengcheng Tu, Xiaoming Lou   +11 more
wiley   +1 more source

Bioactive food components and their inhibitory actions in multiple platelet pathways

Journal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
A comprehensive overview of platelet multifunctional roles in CVD and other diseases and the effects of food components' modulatory effects are described. Abstract In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis ...
Diptimayee Das, Shubhamay Adhikary, Ranjit Kumar Das, Antara Banerjee, Arun Kumar Radhakrishnan, Sujay Paul, Surajit Pathak, Asim K. Duttaroy   +7 more
wiley   +1 more source

Broccoli and Arthritis: A Review

Food Frontiers, EarlyView.
A dietary supplement of broccoli holds potential as a preventive measure against arthritis due to its widespread popularity, safety profile, and affordability. In this systematic review, we have compiled and summarized relevant literature regarding the effects of broccoli and its major bioactive components on arthritis, along with the underlying ...
Mingyuan Song, Xingquan Xu, Prachi Wele, Ding Wei, Xian Wu, Wenjin Yan   +5 more
wiley   +1 more source

AAD-2004, a potent spin trapping molecule and microsomal prostaglandin E synthase-1 inhibitor, shows safety and efficacy in a mouse model of ALS [PDF]

, 2010
While free radicals and inflammation constitute major routes of neuronal injury occurring in neurodegenerative diseases, neither antioxidants nor nonsteroidal anti-inflammatory drugs (NSAIDs) have shown significant efficacy in human clinical trials.
Bok Yun, Byoung Gwag, Doo Im, Jae Lee, Jin Lee, Jin Shin, Joe Springer, Soo Byun, Sun Park, Sun Son, Woong Cho, Yong Lee, Young Lee   +12 more
core   +1 more source

Resolving an inflammatory concept: the importance of inflammation and resolution in tendinopathy [PDF]

, 2014
Injuries to the superficial digital flexor tendon (SDFT) are an important cause of morbidity and mortality in equine athletes, but the healing response is poorly understood.
Abayasekara, Alfredson, Almekinders, Almekinders, Archambault, Astrom, Attur, Attur, Avella, Birch, Christensen, Cohen, Crevier-Denoix, Dakin, Dakin, Dakin, Dowling, Dudhia, Dunn, Evans, Ferry, Funk, Gilroy, Gilroy, Gilroy, Graham, Hosaka, Irvine, Jackson, Jakobsson, Jarvinen, Jayesh Dudhia, Jozsa, Kannus, Ker, Khan, Kojima, Kujala, Lands, Langberg, Leask, Levy, Li, Lin, Longo, Lui, Magra, Marsolais, Millar, Molloy, Morris, Navarro-Xavier, Petrucci, Rajakariar, Riley, Roger K.W. Smith, Ruwanpura, Saito, Serhan, Serhan, Serhan, Serhan, Serhan, Serhan, Serhan, Serhan, Serhan, Serhan, Shrier, Smith, Smith, Stables, Stephanie G. Dakin, Strocchi, Sullo, Sun, Thampatty, Thorpe, Tilley, Tsuzaki, van der Pouw Kraan, Videla, Virchenko, Wang, Webbon, Williams, Wilson, Wynn, Yang, Yang, Ye, Zhang   +91 more
core   +1 more source

Harnessing Jasminum Bioactive Compounds: Updated Insights for Therapeutic and Food Preservation Innovations

Food Frontiers, EarlyView.
Jasminum bioactives improve food preservation by providing antimicrobial and antioxidant effects, especially when incorporated into active packaging, edible films, and nanoformulations that enhance stability and controlled release. They also offer many pharmacological benefits, including anti‐inflammatory, neuroprotective, and wound‐healing properties.
Antonio Rescigno, Paolo Zucca, Stefania Peddio, Sriranjani Srikanth, Niharika Prakash Kaushik, Nanjangud Venkatesh Anil Kumar, Gerardo Leyva‐Gómez, Dorota Kregiel, Ibrahim M. Abu‐Reidah, Surjit Sen, Krishnendu Acharya, William N. Setzer, Marta Palma‐Morales, Miquel Martorell, Daniela Calina, Celia Rodríguez‐Pérez, Javad Sharifi‐Rad, William C. Cho   +17 more
wiley   +1 more source

Mechanistic insights into the primary and secondary alterations of renal ion and water transport in the distal nephron

Journal of Internal Medicine, Volume 293, Issue 1, Page 4-22, January 2023., 2023
Abstract The kidneys, by equilibrating the outputs to the inputs, are essential for maintaining the constant volume, pH, and electrolyte composition of the internal milieu. Inability to do so, either because of internal kidney dysfunction (primary alteration) or because of some external factors (secondary alteration), leads to pathologies of varying ...
Nahid Tabibzadeh, Gilles Crambert
wiley   +1 more source

Identification of Francisella novicida mutants that fail to induce prostaglandin E2 synthesis by infected macrophages.

Frontiers in Microbiology, 2013
Francisella tularensis is the causative agent of tularemia. We have previously shown that infection with F. tularensis Live Vaccine Strain (LVS) induces macrophages to synthesize prostaglandin E2 (PGE2). Synthesis of PGE2 by F.
Matthew Dale Woolard, Lydia M Barrigan, Lydia M Barrigan, James R Fuller, Adam S Buntzman, Joshua eBryan, Colin eManoil, Tom eKawula, Jeffrey A Frelinger   +8 more
doaj   +1 more source

Role of PGE2 in the colonic motility: PGE2 generates and enhances spontaneous contractions of longitudinal smooth muscle in the rat colon

The Journal of Physiological Sciences, 2013
The aim of this study was to determine which PGE2 receptors (EP1-4 receptors) influence colonic motility. Mucosa-free longitudinal smooth muscle strips of the rat middle colon spontaneously induced frequent phasic contractions (giant contractions, GCs) in vitro, and the GCs were almost completely abolished by a cyclooxygenase inhibitor, piroxicam, and ...
Yumiko Iizuka, Shin-ichiro Karaki, Atsukazu Kuwahara   +2 more
openaire   +3 more sources