Results 121 to 130 of about 89,482 (299)
Acta Paediatrica, EarlyView.ABSTRACT Aim This study aimed to investigate the incidence, risk factors and possible aetiology of sudden unexpected postnatal collapse (SUPC), a potentially fatal yet poorly understood event. Methods In a retrospective cohort, patient records from 483 284 infants born in Stockholm, Sweden, between 2002 and 2022 were screened for SUPC‐related diagnoses.
David Forsberg +5 more
wiley +1 more source
Role of PGE2 in Asthma and Nonasthmatic Eosinophilic Bronchitis
, 2012 Eosinophilic bronchitis is a common cause of chronic cough, which like asthma is characterized by sputum eosinophilia, but unlike asthma there is no variable airflow obstruction or airway hyperresponsiveness.
Beatriz Sastre, Victoria del Pozo
core +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
SYNTHESIS OF (–)PGE2 METHYL ESTER AND (–)15-KETO PGE2 METHYL ESTER [PDF]
Proceedings of the Academy of Sciences of the Estonian SSR. Chemistry, 1986 Anne Paju +5 more
openaire +1 more source
PGE2-mediated suppression of IL-15-induced NK cell.
, 2012 (A) PGE2 inhibits the IL-15-induced up-regulation of NKG2D and NKp30 expression. Freshly isolated PBMCs were treated for 48h in medium alone, or in the presence of IL-15 alone (5 ng/ml), or IL-15 (5 ng/ml) plus PGE2 (100 ng/ml), and analyzed on a ...
Sophie Caillat-Zucman (188152) +7 more
core +1 more source
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral +3 more
wiley +1 more source
Involvement of PGE2 in epinephrine signaling.
, 2018 (A) Effect of epinephrine (0.5 mM, 20min) on the activity of the Na+/K+ ATPase in presence of indomethacin (100μM, a COX inhibitor added 20 min before epinephrine; (B) Effect of exogenous PGE2 (1nM,20min) on pump’s activity.
Sawsan I. Kreydiyyeh (4872472) +2 more
core +1 more source
Characterization of PGE2 receptors in isolated rabbit colonic crypt cells
, 1995 The physiological effects of prostaglandins (PG) are mediated through their interactions with specific receptors on effector cells. In this study the properties of PGE2 receptors in the rabbit distal colon were examined.
R. Burakoff, F. R. Homaidan, L. Zhao
core +1 more source
Cell Proliferation, EarlyView.In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar +5 more
wiley +1 more source