Results 201 to 210 of about 89,482 (299)

Phenolic Glycosides From Ficus erecta and Their Anti‐Inflammatory and Neuroprotective Activities

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Five new phenolic glycosides, ficuserectosides A‐E (1–5), along with three known congeners (6–8) were isolated and identified from Ficus erecta. Compounds 5 and 8 protect PC12 cells from oxidative damage by decreasing reactive oxygen species (ROS) and increasing glutathione (GSH), highlighting their potential as neuroprotective leads.
Wenming Wu, Ruiyue Hu, Gang Li, Qinxue Luo, An Jin   +4 more
wiley   +1 more source

Crocus sativus L.-derived lauric acid-functionalized gold nanoparticles induce ferroptosis in HeLa cells and reverse M2 macrophage polarization via the PGE2/EP2/cAMP-PKA signaling pathway: a network pharmacology-based study. [PDF]

Front Pharmacol
Weng J, Liu S, Tong Y, Tang K, Yin L, Bai S, Ou L, Yin Q, Zhou Q.   +8 more
europepmc   +1 more source

A Review of Senescence‐Associated Secretory Phenotype‐Mediated Remodeling of the Tumor Microenvironment: Implications for Cancer Progression and Therapy

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Cellular senescence influences cancer progression through irreversible cell‐cycle arrest, immune surveillance, and paracrine signaling mediated by the senescence‐associated secretory phenotype (SASP). SASP comprises inflammatory cytokines, chemokines, growth factors, and matrix‐remodeling enzymes that regulate the tumor ...
Sneha Pallatt, Sibin Nambidi, Antara Banerjee, Surajit Pathak   +3 more
wiley   +1 more source

Omega-3-Based Nutraceuticals Suppress LPS-Induced Inflammatory Responses in Primary Human Monocytes. [PDF]

Pharmaceuticals (Basel)
Rose T, Schnierle P, Prinzen L, Fiebich BL.   +3 more
europepmc   +1 more source

Inhibition of METTL14 Alleviates OGD/R‐Induced Neuronal Differentiation Injury in Neural Stem Cells Through Suppressing the Tp53inp2/Ptgs2 Axis: Potential Benefits for the Mouse MCAO Model

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
The graphical abstract highlights that ischemic stroke leads to increased METTL14 expression, which enhances Tp53inp2 mRNA stability through m6A modification. Elevated Tp53inp2 then promotes damaging mitophagy and ROS production by upregulating Ptgs2, ultimately impairing the neuronal differentiation of neural stem cells.
Dan Hou, Yujie Hu, Tian Yun, Dan Yu, Guoshuai Yang   +4 more
wiley   +1 more source

Modulating the Gut‐Microbiota‐Brain Axis in Alzheimer's Disease: Therapeutic Potential of Nutritional and Metabolic Factors

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This review systematically examines the role of gut microbiota modulation in Alzheimer's disease, focusing on how microbial metabolites and dietary nutrients influence cognitive function and AD pathology, as well as the neuroprotective effects through the gut‐brain axis.
Binyue Xu, Xuhuan Li, Shangling Dong, Zheyuan Zhang, Dong Jin, Guoping Li, Jiesheng Wang   +6 more
wiley   +1 more source

Helicobacter pylori triggers gastric mucosal remodeling toward a fetal-like transcriptional program via stromal IL-1β signaling. [PDF]

Nat Commun
Beccaceci G, Müllerke S, Berger H, Täger C, Möbius R, Fischer AS, Hartl K, Wizenty J, Mollenkopf HJ, Naumann M, Lin M, Sigal M.   +11 more
europepmc   +1 more source

High PGE₂ Levels Inhibit the Migration of Dendritic Cells by Modulating the PKA-CREB Axis Instead of Epac1-Rap1. [PDF]

Scientifica (Cairo)
Diao G, Huang J, Tian M, Li R, Guo J, Han J.   +5 more
europepmc   +1 more source