Results 251 to 260 of about 133,795 (342)

Advanced Glycation End Products Promote PGE₂ Production in Ca9-22 Cells via RAGE/TLR4-Mediated PKC-NF-κB Pathway. [PDF]

Cells
Ono M, Tanabe N, Ichikawa R, Tomita K, Manaka S, Seki H, Imai Y, Aoki M, Masai Y, Takayama T, Suzuki N, Sato S.   +11 more
europepmc   +1 more source

Defining the Intestinal eCBome and Oxylipin Signaling Systems in a TDP‐43 Mouse Model of Frontotemporal Dementia

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
TDP‐43 overexpressing mice, a genetic model of frontotemporal dementia, exhibit dramatic changes in their small intestinal endocannabinoidome members, in terms of both altered concentrations of lipid mediators and expression of some of their receptors (Cnr1, Gpr119, Gpr55, Pparg) and metabolic enzymes (Napepld, Faah). Also, the levels of some oxylipins
Hayatte‐Dounia Mir, Giada Giorgini, Irene Santos‐García, Elizabeth Dumais, Carmen Rodríguez‐Cueto, Eva de Lago, Cristoforo Silvestri, Nicolas Flamand, Javier Fernández‐Ruiz, Vincenzo Di Marzo   +9 more
wiley   +1 more source

The Effect of Acupuncture on Pain, Prostaglandin E2, and Interleukin-6 in Septorhinoplasty Operations: A Randomized Clinical Trial. [PDF]

Anesthesiol Res Pract
Orak Y, Baylan FA, Bilgen F, Orak F, Ural A, Yildiz S, Sagiroglu S, Karaduman H, Doganer A.   +8 more
europepmc   +1 more source

Unlocking the Therapeutic Potential of Integrin‐Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
3D cancer models provide a more reliable representation of drug responses compared to 2D cell culture owing to their 3D architecture and facilitation of cell‐extracellular matrix interactions. In this study, we engineered dense compartmentalized 3D tumoroids composed of breast tumor mass and a surrounding stromal compartment replicating either breast ...
Salma T. Rafik, Anuja Upadhyay, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Endocannabinoid oxygenation by prostaglandin H synthase-2: Chemistry and biology. [PDF]

J Biol Chem
Rouzer CA, Marnett LJ.
europepmc   +1 more source

Lung Microphysiological System Validates Novel Cell Therapy for Acute Respiratory Distress Syndrome

Advanced Biology, Volume 10, Issue 1, January 2026.
This study aims to evaluate the efficacy of primed mesenchymal stem cells (pMSCs) as an alternative treatment for Acute Respiratory Distress Syndrome (ARDS), based on a novel lung microphysiological system (MPS) to test the efficacy of pMSCs over the standard treatment, Dexamethasone.
Bokyong Kim, So‐Hui Kim, Jieun Kim, Eun‐Young Eo, Hyung‐Jun Kim, Jae Ho Lee, Choon‐Taek Lee, Taeho Kong, Su Kyoung Seo, Seunghee Lee, Jeongbin Park, Young‐Jae Cho   +11 more
wiley   +1 more source

Mathematical models for the EP2 and EP4 signaling pathways and their crosstalk. [PDF]

J Theor Biol
Cambi A, Lidke DS, Ptashnyk M, Smit W, Sonner S.   +4 more
europepmc   +1 more source

Gastroduodenal HCO3− Secretion in Anesthetized Rats: Effects of 16,16-Dimethyl PGE2, Topical Acid and Acetazolamide

, 1986
Koji Takeuchi, Hironori Tanaka, Osamu Furukawa, Susumu Okabe   +3 more
openalex   +1 more source

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, Volume 13, Issue 1, 5 January 2026.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

Light-adaptive interfacial solar steam evaporation enhanced by dynamic water gating. [PDF]

Nat Commun
Wu J, Cui Z, Wu D, Cao Z, Zhang J, Qu J, Hu J, Li J, Tian D, Cai Y.   +9 more
europepmc   +1 more source