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PGE2, PGF2α and catecholaminesinpheochromocytoma
Prostaglandins, Leukotrienes and Medicine, 1982In order to relate urinary prostaglandin excretion in pheochromocytoma /Ph/ to the pattern of noradrenaline /NA/, adrenaline /A/ and dopamine /D/, 14 patients with this disease were investigated during normal sodium intake. 20 healthy volunteers served as controls /C/. Urinary PGs were determined by RIA; NA, A and D were measured fluorometrically.
H. Ignatowska-Switalska +3 more
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Reproduction, fertility, and development, 2001
Diminished PGE2 levels in diabetic embryos are related to the development of malformations, and thus the aim of the present study was to determine whether PGE2 levels are modified in rat embryos cultured in diabetic serum during organogenesis, and if PGE2 content and release, and 3H-PGE2 uptake and release, are altered in incubated diabetic embryos ...
A, Jawerbaum +5 more
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Diminished PGE2 levels in diabetic embryos are related to the development of malformations, and thus the aim of the present study was to determine whether PGE2 levels are modified in rat embryos cultured in diabetic serum during organogenesis, and if PGE2 content and release, and 3H-PGE2 uptake and release, are altered in incubated diabetic embryos ...
A, Jawerbaum +5 more
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The placenta, PGE2 and parturition
Early Human Development, 1992It is proposed that prostaglandin E2 (PGE2), secreted by the fetal placenta of the sheep, acts as a circulating regulator of the physiological function of many fetal organs (tissue) in a way analogous to catecholamines in the adult. The specificity of PGE2 action in different tissues is determined by three different receptor subtypes which regulate ...
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Prostaglandins, 1981
Normal conscious female Sprague-Dawley rats were treated with chlorazanil (3 mg/kg i.p.), and urine was collected for 3 hours. Urine prostaglandin E2-excretion increased from 25 +/- 3 to 271 +/- 32 ng/kg/3 h. The enhancement of urine PGE2-excretion was inhibited by pretreatment with bumetanide (75 mg/kg p.o.).
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Normal conscious female Sprague-Dawley rats were treated with chlorazanil (3 mg/kg i.p.), and urine was collected for 3 hours. Urine prostaglandin E2-excretion increased from 25 +/- 3 to 271 +/- 32 ng/kg/3 h. The enhancement of urine PGE2-excretion was inhibited by pretreatment with bumetanide (75 mg/kg p.o.).
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Preoperative cervical dilatation by oral PGE2
Contraception, 1976Abstract In fifty healthy nulliparous women who underwent therapeutic abortion in the second trimester of pregnancy according to the method of Finks, cervical dilatation has been satisfactorily carried out with PGE 2 -tablets. The average dosage was 3mg.
A S, van den Bergh +2 more
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Prostaglandins, 1975
The biological activities of 8,12-diiso-PGE2 (ent-11,15-epi-PGE2), PGE2 and PGF2alpha have been compared in a series of pharmacological preparations intended to differentiate between F and E type of activity. Similar to PGF2alpha but unlike PGE2, 8,12-diiso-PGE2 increased the tone of isolated smooth muscle preparations of guinea pig trachea, guinea pig
R, Ceserani +3 more
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The biological activities of 8,12-diiso-PGE2 (ent-11,15-epi-PGE2), PGE2 and PGF2alpha have been compared in a series of pharmacological preparations intended to differentiate between F and E type of activity. Similar to PGF2alpha but unlike PGE2, 8,12-diiso-PGE2 increased the tone of isolated smooth muscle preparations of guinea pig trachea, guinea pig
R, Ceserani +3 more
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The Role of PGE2 in Age-related Diseases
Current Drug TargetsIn the past several years, human life expectancy has increased dramatically, and the global aging process is accelerating at an unprecedented rate. Impaired organ functions and systemic inflammation increase the risk of aging-related diseases.
Jun Guan +3 more
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The lung as a privileged site for the beneficial actions of PGE2
Trends in Immunology, 2004Prostaglandin E2 (PGE2) is commonly considered a potent proinflammatory mediator and is involved in several inflammatory diseases. In the lung, as opposed to many other parts of the body, PGE2 has a role in limiting the immune-inflammatory response as well as tissue repair processes.
VANCHERI C +3 more
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PGE2-Gel intrazervikal versus PGE2-Vaginaltabletten: Indikationen, Erfolge und Nebenwirkungen
1988Wahrend die Geburtseinleitung durch Oxytozin heute aus vielerlei Grunden in weit geringerem Umfang Anwendung findet, erlangt die Geburtsinduktion durch Zervixpriming mit lokaler Prostaglandinapplikation in jungerer Zeit sprunghaft zunehmendes Interesse.
F. Wolff, F. Neuhaus, A. Bolte
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Plasma levels of 13,14-dihydro-15-keto PGE2 after vaginal application of a new PGE2 film
Prostaglandins, 1985To determine the release and absorption profile of prostaglandin E2 from a new vaginal film formulation containing 850 micrograms PGE2, serial plasma levels of 13,14-dihydro-15-keto PGE2 were measured by radioimmunoassay in pregnant women between 16 and 18 weeks gestation. A control group, using placebo vaginal film was included in the study. There was
R N, Prasad +4 more
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