Results 21 to 30 of about 296,899 (292)

Tailoring pH-responsive acrylic acid microgels with hydrophobic crosslinks for drug release [PDF]

, 2015
Amphiphilic microgels based on the hydrophilic acrylic acid (AA) and hydrophobic crosslinks of different compositions were synthesised using a lab-on-a-chip device. The microgels were formed by polymerising hydrophobic droplets.
Georgiou, T. K., Lu, B., Pamme, N., Tarn, M. D.   +3 more
core   +2 more sources

pH-Responsive Polymer Nanomaterials for Tumor Therapy

Frontiers in Oncology, 2022
The complexity of the tumor microenvironment presents significant challenges to cancer therapy, while providing opportunities for targeted drug delivery. Using characteristic signals of the tumor microenvironment, various stimuli-responsive drug delivery
Shunli Chu, Xiaolu Shi, Ye Tian, Fengxiang Gao   +3 more
doaj   +1 more source

Self-assembly mechanism of pH-responsive glycolipids : micelles, fibers, vesicles, and bilayers [PDF]

, 2016
A set of four structurally related glycolipids are described: two of them have one glucose unit connected to either stearic or oleic acid, and two other ones have a diglucose headgroup (sophorose) similarly connected to either stearic or oleic acid.
Baccile, Niki, Berton, Jan, Cuvier, Anne-Sophie, Delbeke, Elisabeth, Prévost, Sylvain, Roelants, Sophie, Soetaert, Wim, Stevens, Christian, Van Bogaert, Inge   +8 more
core   +6 more sources

Magnetic Driven Nanocarriers for pH-Responsive Doxorubicin Release in Cancer Therapy

Molecules, 2020
Doxorubicin is one of the most widely used anti-cancer drugs, but side effects and selectivity problems create a demand for alternative drug delivery systems. Herein we describe a hybrid magnetic nanomaterial as a pH-dependent doxorubicin release carrier.
João Nogueira, Sofia F. Soares, Carlos O. Amorim, João S. Amaral, Cláudia Silva, Fátima Martel, Tito Trindade, Ana L. Daniel-da-Silva   +7 more
doaj   +1 more source

A pH-sensitive stearoyl-PEG-poly(methacryloyl sulfadimethoxine)-decorated liposome system for protein delivery: an application for bladder cancer treatment [PDF]

, 2016
Stealth pH-responsive liposomes for the delivery of therapeutic proteins to the bladder epithelium were prepared using methoxy-poly(ethylene glycol)5kDa-1,2-distearoyl-sn-glycero-3-phosphoethanolamine (mPEG5kDa-DSPE) and stearoyl-poly(ethylene glycol ...
Balasso, Anna, Codolo, Gaia, DE BERNARD, Marina, Fassan, Matteo, Malfanti, Alessio, Munari, Fabio, Rugge, Massimo, Salmaso, Stefano, Vila Caballer, Marian   +8 more
core   +1 more source

Eph A10-modified pH-sensitive liposomes loaded with novel triphenylphosphine–docetaxel conjugate possess hierarchical targetability and sufficient antitumor effect both in vitro and in vivo

Drug Delivery, 2018
Mitochondrial-targeting therapy was considered to be a promising approach for the efficient treatment of cancer while positive charge induced nonspecific cytotoxicity severely limits its application.
Jiulong Zhang, Chunrong Yang, Shuang Pan, Menghao Shi, Jie Li, Haiyang Hu, Mingxi Qiao, Dawei Chen, Xiuli Zhao   +8 more
doaj   +1 more source

pH-responsive nanofibers with controlled drug release properties [PDF]

, 2014
Cataloged from PDF version of article.Smart polymers and nanofibers are potentially intriguing materials for controlled release of bioactive agents. This work describes a new class of pH responsive nanofibers for drug delivery systems with controlled ...
Aytac, Z., Celebioglu, A., Demirci, S., Uyar, T.   +3 more
core   +1 more source

Fabrication and Anti-Swelling Properties of Gelatin/Sodium Alginate–Carboxymethyl Chitosan-Based Cationic Coordination Hydrogels

Foods
In this study, the effect of cationic participation on the swelling behavior and pH-responsive release characteristics of polyelectrolyte hydrogel based on gelatin (Gel), sodium alginate (Alg), and carboxymethyl chitosan (CMCS) was explored.
Haixin Zhao, Jinlong Li, Shuang Cong, Hongman Hou, Gongliang Zhang, Jingran Bi   +5 more
doaj   +1 more source

Macrophage Targeting pH Responsive Polymersomes for Glucocorticoid Therapy

Pharmaceutics, 2019
Glucocorticoid (GC) drugs are the cornerstone therapy used in the treatment of inflammatory diseases. Here, we report pH responsive poly(2-methacryloyloxyethyl phosphorylcholine)−poly(2-(diisopropylamino)ethyl methacrylate) (PMPC−PDPA ...
Virgínia M. Gouveia, Loris Rizzello, Claudia Nunes, Alessandro Poma, Lorena Ruiz-Perez, António Oliveira, Salette Reis, Giuseppe Battaglia   +7 more
doaj   +1 more source

pH-Sensitive Mixed Micelles Assembled from PDEAEMA-PPEGMA and PCL-PPEGMA for Doxorubicin Delivery: Experimental and DPD Simulations Study

Pharmaceutics, 2020
To decrease critical micelle concentration (CMC), improve stability, and keep high drug-loading capacity, three pH-sensitive mixed micelles applied for anticancer drug controlled delivery were prepared by the mixture of polymers poly (N,N ...
Chufen Yang, Wenyao Liu, Jiayu Xiao, Cong Yuan, Yaoxi Chen, Jianwei Guo, Hangbo Yue, Dongyu Zhu, Wenjing Lin, Shengqiu Tang, Xiaoying Dong   +10 more
doaj   +1 more source