Results 51 to 60 of about 296,899 (292)
Antibacterial and Cytocompatible pH-Responsive Peptide Hydrogel
A short peptide, FHHF-11, was designed to change stiffness as a function of pH due to changing degree of protonation of histidines. As pH changes in the physiologically relevant range, G′ was measured at 0 Pa (pH 6) and 50,000 Pa (pH 8).
Dona Imanga Upamadi Edirisinghe +9 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Xiangyu Zhang,1 Zelai He2 1Department of Pathology, Jining No.1 People’s Hospital, Jining, Shandong, 272000, People’s Republic of China; 2Department of Radiation Oncology, the First Affiliated Hospital of Bengbu Medical College & Tumor Hospital ...
Zhang X, He Z
doaj
Hemolytic Activity of pH-Responsive Polymer-Streptavidin Bioconjugates [PDF]
Drug delivery systems that increase the rate and/or quantity of drug release to the cytoplasm are needed to enhance cytosolic delivery and to circumvent nonproductive cell trafficking routes. We have previously demonstrated that poly(2-ethylacrylic acid)
Hoffman, Allan S. +5 more
core +1 more source
Reconfigurable pH-Responsive DNA Origami Lattices
AbstractDNA nanotechnology enables straightforward fabrication of user-defined and nano-meter-precise templates for a cornucopia of different uses. To date, most of these DNA assemblies have been static, but dynamic structures are increasingly coming into view.
Linko, Veikko +3 more
openaire +3 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Validation of Smart Nanoparticles as Controlled Drug Delivery Systems: Loading and pH-Dependent Release of Pilocarpine [PDF]
Micelles are good devices for use as controlled drug delivery systems because they exhibit the ability to protect the encapsulated substance from the routes of degradation until they reach the site of action.
Galbis Fuster, Elsa +6 more
core +6 more sources
Yun Bian,1 Dong Guo2 1Department of Pharmacy, Affiliated Hospital of Jiangnan University, The Fourth People’s Hospital of Wuxi City, WuXi 214000, Jiangsu Province, People’s Republic of China; 2Affiliated Hospital of Jiangnan University, The ...
Bian Y, Guo D
doaj
Multifunctional core-shell nanocarriers based on zinc oxide (ZnO)-gated magnetic mesoporous silica nanoparticles (MMSN) were prepared for cancer treatment through magnetic targeting and pH-triggered controlled drug release.
Minchao Liu +8 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

