Results 161 to 170 of about 3,645,606 (296)
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Development of genetically encoded fluorescent sensors for the analysis of mitochondrial pH
reservedIl pH mitocondriale (pHm) è un parametro fondamentale per il corretto funzionamento dei mitocondri e, di conseguenza, per molti processi fisiologici e patologici.
VOLPATO, SIMONE
core
Twisting the Propotypic Molecules of Ph–C≡C–Ph, Ph–CH═CH–Ph, and Ph–N═N–Ph through Cocrystallization
Yury V. Torubaev +3 more
openaire +1 more source
Use of an Alkaline Wastewater Stream to Increase the Initial pH of Whey and Recover a Microbial Biomass with High Protein Content. [PDF]
Pérez-Cortés M +2 more
europepmc +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Bevezetés: A DE ÁOK Szülészeti és Nőgyógyászati Intézetben 2021. júniusában bevezetésre került, szülés utáni köldökzsinór vér rutin vizsgálata óta számos olyan paraméter objektív értékelésére nyílt lehetőség, mely az újszülött születéskori állapotát ...
Csetri, Lehel Csongor
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Protocol for ex vivo physicochemical assessment of photothermally preconditioned platelet-rich plasma. [PDF]
Cordero L +2 more
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source

