Results 121 to 130 of about 2,732,119 (301)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
SISTEM OTOMASI PERAWATAN SENSOR pH PADA PERALATAN MONITORING KADAR pH [PDF]
, 2016 Di Indonesia setiap industri besar di wajibkan memiliki pengolahan limbah yang baik, salah satunya pengolahan limbah cair agar limbah yang dibuang aman untuk lingkungan.
PUTRA, ALDINIO ZULFIKAR MULIA +1 more
core
A targeted fluorescent nanosensor for ratiometric pH sensing at the cell surface
Scientific ReportsThe correlation between altered extracellular pH and various pathological conditions, including cancer, inflammation and metabolic disorders, is well known. Bulk pH measurements cannot report the extracellular pH value at the cell surface. However, there
Charlotte Kromer +5 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
pH sensor calibration procedure [PDF]
, 2013 This paper describes the calibration of pH sensor located at the OBSEA marine Observatory. This instrument is based on an industrial pH electrode that is connected to a CTD instrument (Conductivity, Temperature, and Depth ).
Prat Farran, Joana d'Arc +4 more
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
PVA Nanofibers as an Insoluble pH Sensor. [PDF]
Polymers (Basel), 2023 Mínguez-García D +4 more
europepmc +1 more source
Automation of Orchid Soil pH Using IoT-Based Soil pH Sensor (SKJ-001)
Journal of the Physical Society of IndonesiaThe growth and development process of cymbidium orchids requires a soil pH of around 5.5–6.5. Otherwise, it will cause low nutrient absorption, resulting in yellow leaves and slow growth, while too high a pH can cause the plant's roots to die. Therefore,
Putri Nur Hidayah Komaria +6 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source