Results 131 to 140 of about 2,732,119 (301)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Topology control in Heterogeneous Wireless Sensor Network [PDF]

, 2016
Topology of a Wireless Sensor Network determines the connectivity of the wireless network and topology Control is the important technique of extending network lifetime while preserving network connectivity.
Deshmukh, Prashant, Dandekar, Deepak R
core  

Espial: Electrochemical Soil pH Sensor for In Situ Real-Time Monitoring. [PDF]

Micromachines (Basel), 2023
Eldeeb MA, Dhamu VN, Paul A, Muthukumar S, Prasad S.   +4 more
europepmc   +1 more source

Pengembangan Elektroda Sensor Asam Urat Sebagai Sensor Ph Dengan Penambahan Ruthenium [PDF]

, 2017
pH merupakan salah satu indikator kualitas air, kualitas air penting untuk diketahui karena banyaknya fungsi air yang berdampak langsung pada kehidupan.
PuriArdianti, Tika
core   +1 more source

Single bi-functional flexible sensor device for simultaneous pH and oxygen monitoring during pre-transplant normothermic perfusion

Microsystems & Nanoengineering
Monitoring of organ health and tissue damage through real-time sensing of chemical parameters such as pH and oxygen concentration could provide helpful information in the field of solid organ transplantation. Several sensors have been developed to detect
Avik Sett, Filippos Bersis, Puck Groen, Annelot Muntinga, Jeroen de Jonge, Robbert Friendwijk, Ger de Graaf, Massimo Mastrangeli, Paddy French   +8 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Woolitmus: An Approach to Minimize E-waste using Wool-Based Wearable Sensor for Sweat pH Detection [PDF]

This study introduces "Woolitmus" a textile-based wearable sweat pH indicator developed using pyranine, also known as HPTS (8-Hydroxypyrene-1,3,6-trisulfonic acid) and naturally occurring wool as substrate.
Aditya, Marathe, Ravindra, Adivarekar, Shruti, Ghadge, Sandeep, More   +3 more
core   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source