Results 51 to 60 of about 179,472 (258)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pemantauan pH Produk Skincare berbasis IoT: Solusi untuk Keamanan Konsumen

Edumatic
Skincare products play an important role in skin health, but there is often a discrepancy between the product content and the information on the label, which can harm consumers.
Luntungan Stephen Pieters
doaj   +1 more source

Potentiometric performance of flexible pH sensor based on polyaniline nanofiber arrays

Nano Convergence, 2019
We report potentiometric performance of a polyaniline nanofiber array-based pH sensor fabricated by combining a dilute chemical polymerization and low-cost and simple screen printing process.
Hong Jun Park, Jo Hee Yoon, Kyoung G. Lee, Bong Gill Choi   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Optical sensor for interstitial pH measurements

Journal of Biomedical Optics, 2007
An optical fiber sensor for measuring the pH in interstitial fluid is described. Microdialysis is the approach followed for extracting the sample from the subcutaneous adipose tissue. The interstitial fluid drawn flows through a microfluidic circuit formed by a microdialysis catheter in series with a pH glass capillary. The pH indicator (phenol red) is
Baldini, Francesco, Giannetti, Ambra, Mencaglia, Andrea A.   +2 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Development and Performance of an All-Solid-Stated pH Sensor Based on Modified Membranes

International Journal of Electrochemical Science, 2018
In this study, we developed an all-solid-stated planar pH sensor with the help of magnetron sputtering technology and printed circuit board (PCB). The developed pH sensor consists of a working electrode, which employed antimony sensitive thin film and ...
Kun Xu, Xiliang Zhang, Cheng Chen, Miaomiao Geng   +3 more
doaj   +1 more source

Electronic Sensor for pH Measurements in Nanoliters

Procedia Engineering, 2014
An original design is proposed for the fabrication of an electronic sensor. The device consists on a field effect transistor (FET) combined with an integrated microfluidic channel and is devoted to charges detection in liquids. The technological process has been optimized.
Bouhadda, Ismaïl, de Sagazan, Olivier, Le Bihan, France   +2 more
openaire   +4 more sources