Results 171 to 180 of about 127,368 (296)

Fully Automated Computational Approach for Precisely Measuring Organelle Acidification with Optical pH Sensors. [PDF]

ACS Appl Mater Interfaces, 2022
Chandra A, Chandra A, Prasad S, Alemanno F, De Luca M, Rizzo R, Romano R, Gigli G, Bucci C, Barra A, Del Mercato LL.   +10 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Development of the real-time pH sensing system for array sensors 

, 2020
[[abstract]]This study employs the tin oxide (SnO2) films as the sensing membrane for fabricating array sensors and combines these sensors with a real-time sensing system.
Sun, TP, 孫台平
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Time-Dependent Sensitivity Tunable pH Sensors Based on the Organic-Inorganic Hybrid Electric-Double-Layer Transistor. [PDF]

Int J Mol Sci, 2022
Park KW, Cho WJ.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Flexible Polypyrrole-Based pH Sensors via Oxidative Chemical Vapor Deposition. [PDF]

Adv Healthc Mater
Mukherjee A, Ferrari F, Romero DG, Squillante I, Schoenmaker J, Hemmatpour H, Terpstra A, Dijkstra P, Sayed JE, Koster LJA, Loi MA, Rudolf P, Portale G, Kottapalli AGP, Kamperman M, Bose RK.   +15 more
europepmc   +1 more source

Rapid-Response and Wide-Range pH Sensors Enabled by Self-Assembled Functional PAni/PAA Layer on No-Core Fiber. [PDF]

Materials (Basel), 2022
Long G, Wan L, Xia B, Zhao C, Niu K, Hou J, Lyu D, Li L, Zhu F, Wang N.   +9 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Flexible Inkjet-Printed pH Sensors for Application in Organ-on-a-Chip Biomedical Testing. [PDF]

Biosensors (Basel)
Boček Ž, Dragun DD, Offner L, Krivačić S, Meštrović E, Kassal P.   +5 more
europepmc   +1 more source