Results 171 to 180 of about 43,446 (216)
Some of the next articles are maybe not open access.
Molecular Microbiology, 1996
SummaryThere has recently been great interest in the use of the filamentous bacteriophage fd as a vehicle for the display of peptides and proteins. Phage libraries displaying random peptides up to 38 amino acids in length can be used (i) to select for ligands able to bind specific target molecules; (ii) to mimic non‐proteinaceous ligands; and (iii) as ...
H R, Hill, P G, Stockley
openaire +2 more sources
SummaryThere has recently been great interest in the use of the filamentous bacteriophage fd as a vehicle for the display of peptides and proteins. Phage libraries displaying random peptides up to 38 amino acids in length can be used (i) to select for ligands able to bind specific target molecules; (ii) to mimic non‐proteinaceous ligands; and (iii) as ...
H R, Hill, P G, Stockley
openaire +2 more sources
2009
Phage typing is a rapid, economical, reliable, and reproducible technique, requiring no specialized equipment, for fingerprinting disease-causing agents for epidemiological investigation and surveillance.
Irina, Chirakadze +2 more
openaire +2 more sources
Phage typing is a rapid, economical, reliable, and reproducible technique, requiring no specialized equipment, for fingerprinting disease-causing agents for epidemiological investigation and surveillance.
Irina, Chirakadze +2 more
openaire +2 more sources
Intra-phage immunity: Set a (pro)phage to catch a phage
Cell Host & MicrobeIn this issue, Brenes and Laub screen temperate phages for defenses against other temperate phages. This uncovers an array of prophage-encoded immune systems in E. coli. The work expands the concept of phage-phage conflict, reveals context dependency of defense, and highlights temperate phages as both targets and carriers of anti-phage immunity.
openaire +2 more sources
Synthetic phage and its application in phage therapy
2023Synthetic phage analysis has been implemented in progressive various areas of biology, such as genetics, molecular biology, and synthetic biology. Many phage-derived technologies have been altered for developing gene circuits to program biological systems.
Ajay, Kumar, Anuj, Yadav
openaire +2 more sources
2012
Phage display has emerged as one of the leading technologies for the selection and generation of highly specific antibodies, offering a number of advantages over traditional ways of antibody generation such as mouse hybridoma techniques. While there are various possibilities to conduct phage display, selection of antibodies via solution panning is an ...
openaire +2 more sources
Phage display has emerged as one of the leading technologies for the selection and generation of highly specific antibodies, offering a number of advantages over traditional ways of antibody generation such as mouse hybridoma techniques. While there are various possibilities to conduct phage display, selection of antibodies via solution panning is an ...
openaire +2 more sources
Nature, 1960
A MICRO-ORGANISM identified provisionally as Spirochaeta rosea nom. prov. has been isolated from a marine upper littoral rock-pool at Woods Hole, Mass. The filaments are spiral, 5–200µ long, 0.7µ wide, with a regular pitch of about 7µ and an amplitude of 2µ (Figs. 1 and 2). Transverse cell walls, approximately 2.5µ apart, are revealed by phase-contrast
openaire +2 more sources
A MICRO-ORGANISM identified provisionally as Spirochaeta rosea nom. prov. has been isolated from a marine upper littoral rock-pool at Woods Hole, Mass. The filaments are spiral, 5–200µ long, 0.7µ wide, with a regular pitch of about 7µ and an amplitude of 2µ (Figs. 1 and 2). Transverse cell walls, approximately 2.5µ apart, are revealed by phase-contrast
openaire +2 more sources
2007
The vast majority of novel DNA sequences deposited in the databases now comes from environmental phage DNA sequences. Methods are presented for the cloning and sequencing of phage DNA that might otherwise be lethal to bacterial host vectors or contain modified DNA bases that prevent standard cloning of such sequences. In addition, methods are presented
Veronica, Casas, Forest, Rohwer
openaire +2 more sources
The vast majority of novel DNA sequences deposited in the databases now comes from environmental phage DNA sequences. Methods are presented for the cloning and sequencing of phage DNA that might otherwise be lethal to bacterial host vectors or contain modified DNA bases that prevent standard cloning of such sequences. In addition, methods are presented
Veronica, Casas, Forest, Rohwer
openaire +2 more sources
Phage Choice, Isolation, and Preparation for Phage Therapy
Current Pharmaceutical Biotechnology, 2010Phage therapy is the use of bacteriophages--viruses that use bacteria as their host cells--as biocontrol agents of bacteria. Currently, phage therapy is garnering renewed interest as bacterial resistance to antibiotics becomes widespread. Historically, phage therapy was largely abandoned in the West in the 1940s due to the advent of chemical ...
Jason J, Gill, Paul, Hyman
openaire +2 more sources
Phage DNA subunits in the phage precursor pool
Journal of Molecular Biology, 1961In the presence of chloramphenicol, phage precursor nucleic acid (DNA) can be allowed to accumulate to form a large intrabacterial pool, while protein synthesis has been temporarily arrested. Radiophosphorus, 32 P, of high specific activity was introduced at various stages and, by following the sensitivity to the radioactive 32 P decay of the final ...
A W, KOZINSKI, H, UCHIDA
openaire +2 more sources
Models of phage growth and their applicability to phage therapy
Journal of Theoretical Biology, 2004Phage therapy is complicated by the self-replicating nature of phage. It is difficult to extrapolate from in vitro phage growth data to in vivo expectations, difficult to interpret in vivo data and difficult to generalize from one in vivo situation to another.
Richard J, Weld +2 more
openaire +2 more sources