Results 201 to 210 of about 531,900 (348)

Engineering bacteriophages for gut health: precision antimicrobials and beyond. [PDF]

J Nanobiotechnology
Xu M, Chen S, Pei H, Hu L, Zhang Y.
europepmc   +1 more source

Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion

bioRxiv, 2021
Jeremy Garb, A. Lopatina, A. Bernheim, M. Zaremba, V. Šikšnys, S. Melamed, Azita Leavitt, A. Millman, Gil Amitai, R. Sorek   +9 more
semanticscholar   +1 more source

Advances in Double‐Stranded DNA Targeting Technologies

Exploration, EarlyView.
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen, Yiqun Liu, Yingjie Hao, Yifan Bo, Xiaochuan Dai, Shihui Wang, Tian Xia, Xin Su, Huiyu Liu   +8 more
wiley   +1 more source

Bacteriophage Therapy Against Klebsiella Pneumoniae. [PDF]

Microorganisms
Ding W, Wen Y, Chen L, Du H.
europepmc   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

Food Bioengineering, EarlyView.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi, Panneerselvam Sneha, Dhanapal Saravanan Mridula, Keerthivasan Nimithasree, Valliappan Sanjay   +4 more
wiley   +1 more source

Phage Therapy at the Crossroads Between Clinical Promise and Regulatory Challenge. [PDF]

Pharmaceuticals (Basel)
Gallina A, Gallina M, Cona A, Vitulo P, Mularoni A, Provenzani A.   +5 more
europepmc   +1 more source

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, EarlyView.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

Bentonite-Based Functional Nanoclay Enhances Bacteriophage Therapy against Enteric Infections via Toxin Adsorption and Microbiome Recovery. [PDF]

Biomater Res
Rana MS, Shamsuzzaman M, Shin JH, Lee YJ, Kim B, Seo MG, Seo SM, Kim SH, Lee JC, Kim J, Kim S.   +10 more
europepmc   +1 more source

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

iMeta, EarlyView.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang, Zheng Lin, Runtong Huang, Yang Zhang, Lei Wang, Zan Fu, Chao Wang, Shuai Xiao, Heru Pramono, Kui Xu, Zhimin Xu, Yulong Yin   +11 more
wiley   +1 more source

Chemical inhibition of a bacterial immune system. [PDF]

Cell Host Microbe
Zang Z, Duncan OK, Sabonis D, Fedorova I, Shi Y, Miraj G, Le S, Deng J, Zhu Y, Cai Y, Zhang C, Arya G, Dixon SAH, Angus SP, Duerkop BA, Liang H, Pepin RH, Ve T, Bondy-Denomy J, Tamulaitiene G, Gerdt JP.   +20 more
europepmc   +1 more source