Results 171 to 180 of about 140,627 (227)
Liposome-loaded phage cocktail: a promising therapeutic option against postsurgical wound infections - a critical appraisal. [PDF]
Easwaran M +3 more
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Evaluation of long- and short-term storage conditions and efficiency of a novel microencapsulated Salmonella phage cocktail for controlling Salmonella in chicken meat. [PDF]
Sezer B, Boyaci IH.
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Shopping for phages? Unpacking design rules for therapeutic phage cocktails
Current Opinion in Virology, 2022In bacteriophage therapy, the combination of different phages into a single cocktail is of critical importance to overcome the narrow host range of single phage isolates. Today, the design of therapeutic cocktails is often akin to a black box and relies largely on intuition and (pre-)availability of isolates in local collections.
Cédric Lood +3 more
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Computational design of phage cocktails based on phage-bacteria infection networks
Computers in Biology and Medicine, 2022The misuse and overuse of antibiotics have boosted the proliferation of multidrug-resistant (MDR) bacteria, which are considered a major public health issue in the twenty-first century. Phage therapy may be a promising way in the treatment of infections caused by MDR pathogens, without the side effects of the current available antimicrobials.
Manuel Menor-Flores +2 more
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New Phage cocktail against infantile Sepsis bacteria
Microbial Pathogenesis, 2020A total of 54 positive blood aerobic cultures of suspected blood sepsis in neonates were purified, diagnosed and tested for antibiotic susceptibility. Six bacterial pathogens of Escherichia coli (10 isolates), Klebsiella pneumoniae (10 isolates), Haemophilus influenzae (4 isolates), Pseudomonas aeruginosa (3 isolates), Citrobacter fruendii (1 isolate ...
Sadeq Abdulridha, Gatea Kaabi +1 more
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Host happy hour: Phage cocktail targets IBD-associated microbes
Cell Host & Microbe, 2022Bacteriophage therapy is a promising strategy to treat bacterial infections and sculpt the microbiome. In a recent Cell paper, Federici et al. (2022) demonstrate that a Klebsiella pneumoniae phage cocktail can specifically remove pathobionts from the mouse gut. Safety and persistence of therapeutic phages were shown in a Phase 1 trial.
Jay, Fuerte-Stone, Mark, Mimee
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