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Phage and phage cocktails formulations

2023
Antibiotic-resistant bacterial infection is a major global problem and can be life-threatening. Bacteriophages or phages can be substituted choice over traditional antibiotics treatments. Phages are natural obligate parasites viruses of bacteria, and they can infect and kill antibiotic-sensitive and -resistant bacteria.
openaire   +2 more sources

Phage Cocktail Therapy: Multiple Ways to Suppress Pathogenicity

Trends in Plant Science, 2020
Phage cocktails have emerged as precision tools for controlling plant bacterial diseases. Wang et al. now report that phage cocktails decreased the occurrence of tomato bacterial wilt disease efficiently by infecting and destroying bacterial pathogens, selecting phage-resistant but slow-growing pathogen strains, and fostering bacterial species that are
Na, Liu   +3 more
openaire   +2 more sources

Phage cocktail administration to reduce Salmonella load in broilers.

Research in Veterinary Science
Salmonella is a serious foodborne pathogen that can cause gastrointestinal disease through the consumption of contaminated foods; including poultry meat. Salmonella is commonly present in the intestinal tract of poultry and farm environments, posing a potential risk of contamination during the processing of poultry meat.
Wattana Pelyuntha   +5 more
semanticscholar   +3 more sources

Employment of the Phage Cocktail as a Species-Specific Recognition Agent for Wide-Spectrum Detection of Bacterial Strains.

Analytical Chemistry, 2023
Phages have already been employed to detect bacteria because of their specific recognition capability and strong infectious activity toward their host.
Honglin Yang   +5 more
semanticscholar   +1 more source

Phage therapy with nebulized cocktail BX004-A for chronic Pseudomonas aeruginosa infections in cystic fibrosis: a randomized first-in-human trial

Nature Communications
Cystic fibrosis is a monogenetic disease complicated by recurrent bacterial lung infections that require chronic antibiotics. Pseudomonas aeruginosa is an increasingly antibiotic-resistant pathogen associated with cystic fibrosis morbidity and mortality.
I. Weiner   +43 more
semanticscholar   +1 more source

Phage therapy pharmacology phage cocktails.

Advances in applied microbiology, 2016
Phage therapy is the clinical or veterinary application of bacterial viruses (bacteriophages) as antibacterial "drugs." More generally, phages can be used as biocontrol agents against plant as well as foodborne pathogens. In this chapter, we consider the therapeutic use of phage cocktails, which is the combining of two or more phage types to produce ...
Benjamin K, Chan, Stephen T, Abedon
openaire   +1 more source

Efficacy of two Staphylococcus aureus phage cocktails in cheese production

International Journal of Food Microbiology, 2016
Staphylococcus aureus is one of the most prevalent pathogenic bacteria contaminating dairy products. In an effort to reduce food safety risks, virulent phages are investigated as antibacterial agents to control foodborne pathogens. The aim of this study was to compare sets of virulent phages, design phage cocktails, and use them in a cocktail to ...
Lynn, El Haddad   +6 more
openaire   +2 more sources

Characterization and development of a phage cocktail for Escherichia coli causing gastrointestinal diseases

Journal of Basic and Environmental Sciences
Escherichia coli ( E. coli ) is one of the most important causes of gastrointestinal diseases in developing countries. It considered the third cause of diarrhea in children. In this study, bacteriophages were isolated and detected from wastewater against
Mohamed A. Nasr-Eldin   +4 more
semanticscholar   +1 more source

Evaluation of phage cocktails to prevent avian colibacillosis

2022
Colibacillosis is the main bacterial disease in poultry and is treated mainly by antibiotics, which eventually led to the emergence of antibiotic resistant strains. Our objective was to evaluate the efficacy of two phage cocktails to prevent colibacillosis induced in chicks by the pathogenic strain BEN4358.
Nicolas, Marianne   +7 more
openaire   +1 more source

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