Results 211 to 220 of about 171,183 (250)

Randomized double-blind study on safety and tolerability of TP-102 phage cocktail in patients with infected and non-infected diabetic foot ulcers.

i Medicina
BACKGROUND Phage therapy offers a promising alternative for treating serious infections, including diabetic foot ulcers (DFUs), through the lytic action of phages.
Ran Nir-Paz, H. Onallah, M. Dekel, Y. Gellman, Amir Haze, Ronen Ben-Ami, R. Braunstein, Ronen Hazan, Danna Dror, Y. Oster, Meir Cherniak, Fabienne Attal, Ana R. Barbosa, Helena Dordio, Alexandra Wagner, Daniela Jones-Dias, José Neves, M. Barreto, C. Leandro, Sofia Côrte-Real, Miguel Garcia   +20 more
semanticscholar   +1 more source

Characterization of novel Erwinia amylovora-specific phiEaSP1 phage and its application as phage cocktail for managing fire blight in apples.

Microbiology Research
Erwinia amylovora (Ea) is a devastating bacterial pathogen that causes fire blight disease in Rosaceae family plants, including apples and pears. The use of bacteriophages is an alternative strategy to antibiotics for managing bacterial pathogens.
Hyeongsoon Kim, N. Vu, Roniya Thapa Magar, Eom-Ji Oh, Ki‐Hoon Oh, Jiwon Lee, Lee-Seul Kim, In Sun Hwang, Chang-Sik Oh   +8 more
semanticscholar   +1 more source

Phage therapy pharmacology phage cocktails.

Advances in applied microbiology, 2016
Phage therapy is the clinical or veterinary application of bacterial viruses (bacteriophages) as antibacterial "drugs." More generally, phages can be used as biocontrol agents against plant as well as foodborne pathogens. In this chapter, we consider the therapeutic use of phage cocktails, which is the combining of two or more phage types to produce ...
Benjamin K, Chan, Stephen T, Abedon
openaire   +1 more source

Phage therapy with nebulized cocktail BX004-A for chronic Pseudomonas aeruginosa infections in cystic fibrosis: a randomized first-in-human trial

Nature Communications
Cystic fibrosis is a monogenetic disease complicated by recurrent bacterial lung infections that require chronic antibiotics. Pseudomonas aeruginosa is an increasingly antibiotic-resistant pathogen associated with cystic fibrosis morbidity and mortality.
I. Weiner, M. Kahan-Hanum, Nufar Buchstab, L. Zelcbuch, Sharon Navok, Irit Sherman, J. Nicenboim, T. Axelrod, D. Berko-Ashur, Maya Olshina, R. Mordoch, J. Jablonska, Tamar Gera-Inbar, Ilya Vainberg-Slutskin, Britny Blumenfeld, Hila Sberro-Livnat, A. Moses, Hadas Nevenzel, I. Levy-Saar, Jenia Gold, M. Goldberg, Nina Tchernorudsky, Noa Ben-Yishay, T. Cohen, Edith Kario, Inesa Levovich, R. Safonov, Y. Tzur, Y. Zarchin, V. Lev, Yifat Elharar, Einav Safyon-Gartman, I. Gahali-Sass, S. Puttagunta, X. Ussery, R. Vilchez, U. Rappo, N. Zak, M. Golembo, Ariel Cohen, J. Koff, Eitan Kerem, R. Sorek, M. Bassan   +43 more
semanticscholar   +1 more source

Efficacy of two Staphylococcus aureus phage cocktails in cheese production

International Journal of Food Microbiology, 2016
Staphylococcus aureus is one of the most prevalent pathogenic bacteria contaminating dairy products. In an effort to reduce food safety risks, virulent phages are investigated as antibacterial agents to control foodborne pathogens. The aim of this study was to compare sets of virulent phages, design phage cocktails, and use them in a cocktail to ...
Lynn, El Haddad, Jean-Pierre, Roy, Georges E, Khalil, Daniel, St-Gelais, Claude P, Champagne, Steve, Labrie, Sylvain, Moineau   +6 more
openaire   +2 more sources

Safety and efficacy of a phage cocktail on murine wound infections caused by carbapenem-resistant Klebsiella pneumoniae.

International Journal of Antimicrobial Agents
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a leading pathogen causing difficult-to-treat, healthcare-associated wound infections. Phages are an alternative approach against CRKP. We established murine wound infection models with a CRKP clinical
Yan Feng, Qingqing Fang, Huan Luo, Juan Li, Xin Yin, Z. Zong   +5 more
semanticscholar   +1 more source

Computational prediction of a phage cocktail active against multidrug-resistant bacteria

F1000Research
Background Antibiotic misuse and overuse have contributed to the emergence of multi-drug resistant (MDR) bacteria, posing a serious public health problem across the globe.
Rabia Nawaz, Ali Husnain, Muhammad Ali Arif, Zohal Hassan, A. Ahad, Hafsa Amat Ur Rasool, Muhammad Shahid, Uqba Mehmood, Attia Razzaq, Muhammad Idrees, Wayne G.Carter   +10 more
semanticscholar   +1 more source

Characterization and efficacy of Salmonella phage cocktail PHA46 in the control of Salmonella Newport and Typhimurium internalized into cherry tomatoes.

Journal of food microbiology
Non-typhoid Salmonella enterica causes salmonellosis illness, and this bacterium can contaminate food throughout the production chain, including those that are consumed as raw products. Salmonella enterica can adhere to and internalize into fresh produce
Aurora Dolores Arista‐Regalado, Oliver Viera-Segura, Saúl Aguilar-Montes de Oca, Leonardo Hernández-Hernández, D. González-Aguilar, Jeannette Barba León   +5 more
semanticscholar   +1 more source

Phage cocktail superimposed disinfection: A ecological strategy for preventing pathogenic bacterial infections in dairy farms.

Environmental Research
Bovine mastitis (BM) is mainly caused by bacterial infection that has a highly impact on dairy production, affecting both economic viability and animal well-being.
Yibing Xue, Ya Gao, Mengting Guo, Yumin Zhang, Guoqing Zhao, Lu Xia, Jingjiao Ma, Yuqiang Cheng, Hengan Wang, Jianhe Sun, Zhaofei Wang, Yaxian Yan   +11 more
semanticscholar   +1 more source

Evaluation of phage cocktails to prevent avian colibacillosis

2022
Colibacillosis is the main bacterial disease in poultry and is treated mainly by antibiotics, which eventually led to the emergence of antibiotic resistant strains. Our objective was to evaluate the efficacy of two phage cocktails to prevent colibacillosis induced in chicks by the pathogenic strain BEN4358.
Nicolas, Marianne, Menanteau, Pierrette, Girault, Mylène, Faurie, Arnaud, Chaumeil, Thierry, Riou, Mickaël, Velge, Philippe, Schouler, Catherine   +7 more
openaire   +1 more source