Results 1 to 10 of about 189,366 (255)

An efficient CRISPR-Cas12a tool for iterative genome editing, streamlined minimization, and payload engineering of Pseudomonas phage S1 [PDF]

Synthetic and Systems Biotechnology
The ability to precisely engineer phage genomes is critical for advancing phage-based biotechnology and therapeutic development. Here, we present a high-efficiency, scarless CRISPR-Cas12a genome editing method for a virulent Pseudomonas aeruginosa phage ...
Yanmei Liu, Zizhen Liang, Yanyun Jing, Yanrui Ye, Xiaofeng Yang, Zhanglin Lin   +5 more
doaj   +2 more sources

Isolation and genomic analysis of phage BUCT551 against drug-resistant Aeromonas hydrophila [PDF]

Frontiers in Veterinary Science
Aeromonas hydrophila (A. hydrophila) is a common pathogen in aquaculture that also causes opportunistic infections and sporadic food- and water-borne illness in humans.
Pengjun Han, Pengjun Han, Hongbo Qin, Chenxi Hao, Zhiping Du, Yang Yang, Yang Yang   +6 more
doaj   +2 more sources

GenomeFingerprinter and universal genome fingerprint analysis for systematic comparative genomics [PDF]

, 2013
How to compare whole genome sequences at large scale has not been achieved via conventional methods based on pair-wisely base-to-base comparison; nevertheless, no attention was paid to handle in-one-sitting a number of genomes crossing genetic category ...
Ai, Hannan, Ai, Yuncan, Meng, Fanmei, Zhao, Lei   +3 more
core   +17 more sources

Modeling the fitness consequences of a cyanophage-encoded photosynthesis gene. [PDF]

PLoS ONE, 2008
BACKGROUND: Phages infecting marine picocyanobacteria often carry a psbA gene, which encodes a homolog to the photosynthetic reaction center protein, D1. Host encoded D1 decays during phage infection in the light.
Jason G Bragg, Sallie W Chisholm
doaj   +1 more source

First Characterization of a Hafnia Phage Reveals Extraordinarily Large Burst Size and Unusual Plaque Polymorphism

Frontiers in Microbiology, 2022
A unique lytic phage infecting Hafnia paralvei was isolated and identified. Hafnia phage Ca belongs to the family Autographiviridae, possessing an icosahedral head with a diameter of 55 nm and a short non-contractile tail.
Lingting Pan, Lingting Pan, Dengfeng Li, Zhitong Sun, Wei Lin, Wei Lin, Binxin Hong, Weinan Qin, Lihua Xu, Wencai Liu, Qin Zhou, Fei Wang, Ruqian Cai, Minhua Qian, Yigang Tong   +14 more
doaj   +1 more source

Properties of Pseudomonas aeruginosa Phage K4 and Its Applications in Food Preservation

Shipin gongye ke-ji, 2022
Objective: To study phage applications in the control of bacteria contaminations, Pseudomonas aeruginosa phage K4 was characterized for its biological characteristics and inhibition effects of bacterial growth.
Wenjing PANG, Qingzhu HAN, Jiajia YOU, Donghang LI, Peize LI, Yueying LI, Hongjiang YANG   +6 more
doaj   +1 more source

Characterization of a lytic Pseudomonas aeruginosa phage vB_PaeP_ASP23 and functional analysis of its lysin LysASP and holin HolASP

Frontiers in Microbiology, 2023
In this study, we isolated a lytic Pseudomonas aeruginosa phage (vB_PaeP_ASP23) from the sewage of a mink farm, characterized its complete genome and analyzed the function of its putative lysin and holin.
Jiaqi Cui, Xiaojie Shi, Xinwei Wang, Huzhi Sun, Yanxin Yan, Feiyang Zhao, Can Zhang, Wenhua Liu, Ling Zou, Lei Han, Qiang Pan, Huiying Ren   +11 more
doaj   +1 more source

Virulent Drexlervirial Bacteriophage MSK, Morphological and Genome Resemblance With Rtp Bacteriophage Inhibits the Multidrug-Resistant Bacteria

Frontiers in Microbiology, 2021
Phage-host interactions are likely to have the most critical aspect of phage biology. Phages are the most abundant and ubiquitous infectious acellular entities in the biosphere, where their presence remains elusive. Here, the novel Escherichia coli lytic
Muhammad Saleem Iqbal Khan, Xiangzheng Gao, Keying Liang, Shengsheng Mei, Jinbiao Zhan   +4 more
doaj   +1 more source

Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages [PDF]

, 2020
Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo bacteriophage to investigate phage-bacteria interactions and is a candidate for phage therapy applications.
Blasdel, Bob G., Briers, Yves, Danis‐Wlodarczyk, Katarzyna, Drulis‐Kawa, Zuzanna, Jang, Ho Bin, Lavigne, Rob, Lood, Cédric, Noben, Jean‐Paul, Noort, Vera, Vandenheuvel, Dieter   +9 more
core   +1 more source

Genome Analysis and Therapeutic Evaluation of a Novel Lytic Bacteriophage of Salmonella Typhimurium: Suggestive of a New Genus in the Subfamily Vequintavirinae

Viruses, 2022
Salmonella Typhimurium, a foodborne pathogen, is a major concern for food safety. Its MDR serovars of animal origin pose a serious threat to the human population. Phage therapy can be an alternative for the treatment of such MDR Salmonella serovars.
Sadia Sattar, Inam Ullah, Sofia Khanum, Marc Bailie, Bushra Shamsi, Ibrar Ahmed, Tahir Abbas Shah, Sundus Javed, Aamir Ghafoor, Amna Pervaiz, Fakiha Sohail, Kaleem Imdad, Aamira Tariq, Nazish Bostan, Ijaz Ali, Eric Altermann   +15 more
doaj   +1 more source