Results 41 to 50 of about 126,149 (256)

Genome Sequence of Salmonella Phage 9NA [PDF]

Genome Announcements, 2014
ABSTRACT The virulent double-stranded DNA (dsDNA) bacteriophage 9NA infects Salmonella enterica serovar Typhimurium and has a long noncontractile tail. We report its complete 52,869-bp genome sequence. Phage 9NA and two closely related S.
Casjens, Sherwood R., Leavitt, Justin C., Hatfull, Graham F., Hendrix, Roger W.   +3 more
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Genome Sequence of Gordonia Phage BetterKatz [PDF]

Genome Announcements, 2016
ABSTRACT BetterKatz is a bacteriophage isolated from a soil sample collected in Pittsburgh, Pennsylvania using the host Gordonia terrae 3612. BetterKatz's genome is 50,636 bp long and contains 75 predicted protein-coding genes, 35 of which have been assigned putative functions.
Pope, Welkin H., Berryman, Emily N., Forrest, Kaitlyn M., McHale, Lilliana, Wertz, Anthony T., Zhuang, Zenas, Kasturiarachi, Naomi S., Pressimone, Catherine A., Schiebel, Johnathon G., Furbee, Emily C., Grubb, Sarah R., Warner, Marcie H., Montgomery, Matthew T., Garlena, Rebecca A., Russell, Daniel A., Jacobs-Sera, Deborah, Hatfull, Graham F.   +16 more
openaire   +2 more sources

Genome Analysis and Antibiofilm Activity of Phage 590B against Multidrug-Resistant and Extensively Drug-Resistant Uropathogenic Escherichia coli Isolates, India

Pathogens, 2022
Urinary tract infections (UTIs) are among the most common bacterial infections in humans. Uropathogenic Escherichia coli (UPEC), which are the most frequent agents causing community as well as hospital-acquired UTIs, have become highly drug-resistant ...
Naveen Chaudhary, Ravi Kumar Maurya, Dharminder Singh, Balvinder Mohan, Neelam Taneja   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Evolutionary Stability of a Refactored Phage Genome

ACS Synthetic Biology, 2012
Engineered genetic systems are commonly unstable; if propagated, they evolve to reverse or modify engineered elements because the elements impair fitness. A goal of synthetic biology is thus to anticipate and avoid detrimental engineering, but little is yet known about which types of elements cause problems in different contexts.
Springman, Rachael, Molineux, Ian J., Duong, Chanan, Bull, Robert J., Bull, James J.   +4 more
openaire   +2 more sources

Vibrio choleraePhage K139: Complete Genome Sequence and Comparative Genomics of Related Phages [PDF]

Journal of Bacteriology, 2002
ABSTRACTIn this report, we characterize the complete genome sequence of the temperate phage K139, which morphologically belongs to theMyoviridaephage family (P2 and 186). The prophage genome consists of 33,106 bp, and the overall GC content is 48.9%. Forty-four open reading frames were identified.
Dagmar, Kapfhammer, Julia, Blass, Stefan, Evers, Joachim, Reidl   +3 more
openaire   +2 more sources

A reverse transcriptase controls prophage genome reduction to promote phage dissemination in Pseudomonas aeruginosa biofilms

Cell Reports
Summary: Filamentous bacteriophages play a critical role in biofilm formation and virulence in the opportunistic pathogen Pseudomonas aeruginosa. Here, studies of the filamentous Pf4 prophage life cycle within P.
Yunxue Guo, Shituan Lin, Ran Chen, Jiayu Gu, Kaihao Tang, Zhaolong Nie, Zixian Huang, Juehua Weng, Jianzhong Lin, Tianlang Liu, Matthew K. Waldor, Xiaoxue Wang   +11 more
doaj   +1 more source

The Podovirus ϕ80-18 Targets the Pathogenic American Biotype 1B Strains of Yersinia enterocolitica

Frontiers in Microbiology, 2020
We report here the complete genome sequence and characterization of Yersinia bacteriophage vB_YenP_ϕ80-18. ϕ80-18 was isolated in 1991 using a Y. enterocolitica serotype O:8 strain 8081 as a host from a sewage sample in Turku, Finland, and based on its ...
Karolina Filik, Bożena Szermer-Olearnik, Maciej Wernecki, Lotta J. Happonen, Maria I. Pajunen, Ayesha Nawaz, Muhammad Suleman Qasim, Jin Woo Jun, Laura Mattinen, Mikael Skurnik, Mikael Skurnik, Ewa Brzozowska   +11 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source