Results 61 to 70 of about 1,053,752 (301)

A reverse transcriptase controls prophage genome reduction to promote phage dissemination in Pseudomonas aeruginosa biofilms

Cell Reports
Summary: Filamentous bacteriophages play a critical role in biofilm formation and virulence in the opportunistic pathogen Pseudomonas aeruginosa. Here, studies of the filamentous Pf4 prophage life cycle within P.
Yunxue Guo, Shituan Lin, Ran Chen, Jiayu Gu, Kaihao Tang, Zhaolong Nie, Zixian Huang, Juehua Weng, Jianzhong Lin, Tianlang Liu, Matthew K. Waldor, Xiaoxue Wang   +11 more
doaj   +1 more source

The Podovirus ϕ80-18 Targets the Pathogenic American Biotype 1B Strains of Yersinia enterocolitica

Frontiers in Microbiology, 2020
We report here the complete genome sequence and characterization of Yersinia bacteriophage vB_YenP_ϕ80-18. ϕ80-18 was isolated in 1991 using a Y. enterocolitica serotype O:8 strain 8081 as a host from a sewage sample in Turku, Finland, and based on its ...
Karolina Filik, Bożena Szermer-Olearnik, Maciej Wernecki, Lotta J. Happonen, Maria I. Pajunen, Ayesha Nawaz, Muhammad Suleman Qasim, Jin Woo Jun, Laura Mattinen, Mikael Skurnik, Mikael Skurnik, Ewa Brzozowska   +11 more
doaj   +1 more source

Genome Analysis and Antibiofilm Activity of Phage 590B against Multidrug-Resistant and Extensively Drug-Resistant Uropathogenic Escherichia coli Isolates, India

Pathogens, 2022
Urinary tract infections (UTIs) are among the most common bacterial infections in humans. Uropathogenic Escherichia coli (UPEC), which are the most frequent agents causing community as well as hospital-acquired UTIs, have become highly drug-resistant ...
Naveen Chaudhary, Ravi Kumar Maurya, Dharminder Singh, Balvinder Mohan, Neelam Taneja   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Genome Sequence of Salmonella Phage 9NA [PDF]

Genome Announcements, 2014
ABSTRACT The virulent double-stranded DNA (dsDNA) bacteriophage 9NA infects Salmonella enterica serovar Typhimurium and has a long noncontractile tail. We report its complete 52,869-bp genome sequence. Phage 9NA and two closely related S.
Casjens, Sherwood R., Leavitt, Justin C., Hatfull, Graham F., Hendrix, Roger W.   +3 more
openaire   +2 more sources

Genome Characterization of a Novel Wastewater Bacteroides fragilis Bacteriophage (vB_BfrS_23) and its Host GB124

Frontiers in Microbiology, 2020
Bacteroides spp. are part of the human intestinal microbiota but can under some circumstances become clinical pathogens. Phages are a potentially valuable therapeutic treatment option for many pathogens, but phage therapy for pathogenic Bacteroides spp ...
Mohammad A. Tariq, Fiona Newberry, Fiona Newberry, Rik Haagmans, Rik Haagmans, Catherine Booth, Tom Wileman, Tom Wileman, Lesley Hoyles, Martha R. J. Clokie, James Ebdon, Simon R. Carding, Simon R. Carding   +12 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Genome Sequence of Gordonia Phage BetterKatz [PDF]

Genome Announcements, 2016
ABSTRACT BetterKatz is a bacteriophage isolated from a soil sample collected in Pittsburgh, Pennsylvania using the host Gordonia terrae 3612. BetterKatz's genome is 50,636 bp long and contains 75 predicted protein-coding genes, 35 of which have been assigned putative functions.
Pope, Welkin H., Berryman, Emily N., Forrest, Kaitlyn M., McHale, Lilliana, Wertz, Anthony T., Zhuang, Zenas, Kasturiarachi, Naomi S., Pressimone, Catherine A., Schiebel, Johnathon G., Furbee, Emily C., Grubb, Sarah R., Warner, Marcie H., Montgomery, Matthew T., Garlena, Rebecca A., Russell, Daniel A., Jacobs-Sera, Deborah, Hatfull, Graham F.   +16 more
openaire   +2 more sources

Whole genome sequencing and in vitro activity data of Escherichia phage NTEC3 against multidrug-resistant Uropathogenic and extensively drug-resistant Uropathogenic E. coli isolates

Data in Brief, 2022
This data article describes the whole-genome sequencing and in vitro activity data of Escherichia phage NTEC3 isolated from a community sewage sample in Chandigarh, India. The phage NTEC3 was active against multi-drug-resistant (MDR) and extensively drug-
Naveen Chaudhary, Dharminder Singh, Ravi Kumar Maurya, Balvinder Mohan, Ravimohan S. Mavuduru, Neelam Taneja   +5 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source