Results 81 to 90 of about 125,595 (262)

Genomic characterization of APEC phages and evaluation of the efficacy in reducing the loads of APEC O78 infections in chickens

Frontiers in Microbiology
IntroductionThe resistance of avian pathogenic Escherichia coli (APEC) poses a serious challenge to the control of bacterial diseases in the poultry industry.
Qin Lu, Xinxin Jin, Xinxin Jin, Zui Wang, Rongrong Zhang, Rongrong Zhang, Yunqing Guo, Yunqing Guo, Qiao Hu, Qiao Hu, Wenting Zhang, Wenting Zhang, Tengfei Zhang, Tengfei Zhang, Qingping Luo, Qingping Luo, Qingping Luo   +16 more
doaj   +1 more source

Combining Comprehensive Analysis of Off-Site Lambda Phage Integration with a CRISPR-Based Means of Characterizing Downstream Physiology

mBio, 2017
During its lysogenic life cycle, the phage genome is integrated into the host chromosome by site-specific recombination. In this report, we analyze lambda phage integration into noncanonical sites using next-generation sequencing and show that it ...
Yu Tanouchi, Markus W. Covert
doaj   +1 more source

Isolation and Characterization of Salmonella Jumbo-Phage pSal-SNUABM-04

Viruses, 2020
The increasing emergence of antimicrobial resistance has become a global issue. Therefore, many researchers have attempted to develop alternative antibiotics. One promising alternative is bacteriophage.
Jun Kwon, Sang Guen Kim, Hyoun Joong Kim, Sib Sankar Giri, Sang Wha Kim, Sung Bin Lee, Se Chang Park   +6 more
doaj   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

A novel tail fiber protein triggers phage DNA ejection by recognizing lipopolysaccharides of K54 hypervirulent Klebsiella pneumoniae

Microbiology Spectrum
Bacteriophage (phage) therapy is a promising alternative antibacterial approach for treating infectious diseases by hvKp. However, there has been a lack of studies on the host recognition and infection initiation of hvKp phages.
Ming Yin, Li Cao, Yu Fu, Yanjun Lu, Yi Yan, Lvxin Qian, Li Xiang, Tiejun Zhou, Huan Chen, Ying Li, Luhua Zhang   +10 more
doaj   +1 more source

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease

Annals of Neurology, EarlyView.
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh, Xochitl C. Morgan, Jordan Jensen, Kjetil Bjornevik, Michael A. Schwarzschild, Alberto Ascherio, Curtis Huttenhower, Natalia Palacios   +7 more
wiley   +1 more source

Complete Genome of the Xanthomonas euvesicatoria Specific Bacteriophage KΦ1, Its Survival and Potential in Control of Pepper Bacterial Spot

Frontiers in Microbiology, 2018
Xanthomonas euvesicatoria phage KΦ1, a member of Myoviridae family, was isolated from the rhizosphere of pepper plants showing symptoms of bacterial spot. The phage strain expressed antibacterial activity to all X.
Katarina Gašić, Nemanja Kuzmanović, Milan Ivanović, Anđelka Prokić, Milan Šević, Aleksa Obradović   +5 more
doaj   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Comprehensive analysis of phage genomes from diverse environments reveals their diversity, potential applications, and interactions with hosts and other phages

Frontiers in Microbiology
Phages are ubiquitous and diverse, playing a key role in maintaining microbial ecosystem balance. However, their diversity, potential applications, and their interactions with hosts and other phages remain largely unexplored.
Chao Wei, Zhe Chen
doaj   +1 more source

Phage Genomics [PDF]

Cell, 2002
Brüssow, Harald, Hendrix, Roger W.
openaire   +1 more source