Results 91 to 100 of about 126,149 (256)
Phages are ubiquitous and diverse, playing a key role in maintaining microbial ecosystem balance. However, their diversity, potential applications, and their interactions with hosts and other phages remain largely unexplored.
Chao Wei, Zhe Chen
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During its lysogenic life cycle, the phage genome is integrated into the host chromosome by site-specific recombination. In this report, we analyze lambda phage integration into noncanonical sites using next-generation sequencing and show that it ...
Yu Tanouchi, Markus W. Covert
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Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley +1 more source
Genome Sequence of Mycobacterium Phage Guppsters.
Mycobacterium Phage Guppsters was isolated on Mycobacterium smegmatis mc 2 155, displays a siphovirus morphology, and possesses a 54,835 base pair genome. Based on gene content similarity, Guppsters is assigned to cluster F1. Unlike a majority of F1 phages, Guppsters does not encode mycobacteriophage mobile elements.
Alley, Emma K +13 more
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The complete genome of Escherichia phage Midge
ABSTRACT In this report, we describe the isolation and genomic annotation of Escherichia phage Midge. A P2-like myophage, Midge, has a 29,617 bp genome.
Paige Ripberger +2 more
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Harmful Microcystis proliferation severely threatens aquatic ecosystems globally, but its impacts on food‐web stability remain poorly understood. Here, we analyzed 1309 metagenomic samples from freshwater ecosystems across China to investigate how Microcystis abundance affects synchrony among taxa in multi‐trophic food webs (from bacteriophages to ...
Lemian Liu +6 more
wiley +1 more source
Isolation and genomic analysis of phage BUCT551 against drug-resistant Aeromonas hydrophila
Aeromonas hydrophila (A. hydrophila) is a common pathogen in aquaculture that also causes opportunistic infections and sporadic food- and water-borne illness in humans.
Pengjun Han +6 more
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Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar +4 more
wiley +1 more source
Genome sequence of Microbacterium phage Casino
ABSTRACT We present the genome of Casino, a lytic actinobacteriophage assigned to the EM1 subcluster. Casino infects Microbacterium foliorum NRRL B-24224 and was isolated from a soil sample in Storrs, Connecticut. The genome is 53,667 bp in length with 48 annotated genes and
Jennifer H. Arca +19 more
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