Results 101 to 110 of about 1,053,752 (301)

Comparative Genomic Analysis of 130 Bacteriophages Infecting Bacteria in the Genus Pseudomonas

Frontiers in Microbiology, 2018
Bacteria of the genus Pseudomonas are genetically diverse and ubiquitous in the environment. Like other bacteria, those of the genus Pseudomonas are susceptible to bacteriophages which can significantly affect their host in many ways, ranging from cell ...
Anh D. Ha, Dee R. Denver
doaj   +1 more source

Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]

, 2007
A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Camacho, F., Perez, E.M., Amin, N., Aguilar, A., David I. Stott, Talavera, A., Arturo Talavera, Raiza Martinez, Frank Camacho, Nevis Amin, Ela M. Perez, Larralde, O.G., Alicia Aguilar, Martinez, R., Osmany G. Larralde, Stott, D.I.   +15 more
core   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Isolation of A Novel Bacillus thuringiensis Phage Representing A New Phage Lineage and Characterization of Its Endolysin

Viruses, 2018
Phages, the parasites of bacteria, are considered as a new kind of antimicrobial agent due to their ability to lyse pathogenic bacteria. Due to the increase of available phage isolates, the newly isolated phage showed increasing genomic similarities with
Yihui Yuan, Qin Peng, Shuo Yang, Shaowen Zhang, Yajuan Fu, Yan Wu, Meiying Gao   +6 more
doaj   +1 more source

Complete genome sequences of four novel Lactococcus lactis phages distantly related to the Rare 1706 Phage Species [PDF]

, 2014
Lactoccocus lactis is a Gram-positive bacterium widely used in the dairy industry in the production of an array of cheeses and other fermented milk products.
Neve, Horst, Hansen, Lars H., Heller, Knut J, Sørensen, Søren Johannes, Vogensen, Finn Kvist, Kot, Witold Piotr, Kot, Witold, Vogensen, Finn K., Sörensen, Sören J., Heller, Knut   +9 more
core   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

Advanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park, Yeongkag Kwon, Yeonjin Lim, Jeong Woo Park, Hyun Jung Ji, Dongwook Lee, Jueun Lee, Sung‐Ho Yun, Sungho Jeong, Ho Seong Seo, Kun Cho, Cheol‐Heui Yun, Ok‐Jin Park, Seung Hyun Han   +13 more
wiley   +1 more source

Genomic characterization of APEC phages and evaluation of the efficacy in reducing the loads of APEC O78 infections in chickens

Frontiers in Microbiology
IntroductionThe resistance of avian pathogenic Escherichia coli (APEC) poses a serious challenge to the control of bacterial diseases in the poultry industry.
Qin Lu, Xinxin Jin, Xinxin Jin, Zui Wang, Rongrong Zhang, Rongrong Zhang, Yunqing Guo, Yunqing Guo, Qiao Hu, Qiao Hu, Wenting Zhang, Wenting Zhang, Tengfei Zhang, Tengfei Zhang, Qingping Luo, Qingping Luo, Qingping Luo   +16 more
doaj   +1 more source

Genome Sequence of the Pseudomonas protegens Phage ΦGP100

, 2018
We report here the complete annotated genome sequence of ΦGP100, a lytic bacteriophage of the Podoviridae family. ΦGP100 was isolated from rhizosphere soil in Switzerland and infects specifically strains of Pseudomonas
Peter Kupferschmied, Vacheron, J., Grégory Resch, Jordan Vacheron, Resch, G., Christoph Keel, Keel, C., Kupferschmied, P., Vacheron J, Kupferschmied, Peter, Vacheron, Jordan, Resch, Grégory, Kupferschmied P, Resch G, Keel C, Keel, Christoph   +15 more
core   +1 more source

Tightening Bonds in Latin America Through Phage Discovery

, 2021
Between 2015 and 2019, we hosted an International Phage Course at Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina.
Rondón Salazar, Liliana, Payaslian, Florencia Pía, Reyes, Alejandro, Urdániz, Estefanía, Gradaschi, Victoria, Allievi, Mariana, Allievi, Mariana Caludia, Raya, Raúl Ricardo, Sanchez Rivas, Carmen, Zon, Fabio, Piuri, Mariana, Payaslian, Florencia, Dieterle, Maria Eugenia, Di Paola, Matias, Di Paola, Matías Ezequiel, Florencia Payaslian, Victoria Gradaschi, Carmen Sanchez Rivas, Mariana Allievi, Mariana Piuri, Maria Eugenia Dieterle, Alejandro Reyes, Fabio Zon, Estefanía Urdániz, Matias Di Paola, Raúl Ricardo Raya, Liliana Rondón Salazar   +26 more
core   +1 more source

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

Advanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu, Jun Yang, Yuhang Zhang, Xiaoli Xue   +3 more
wiley   +1 more source