Results 121 to 130 of about 190,753 (310)
Improved single-swab sample preparation for recovering bacterial and phage DNA from human skin and wound microbiomes. [PDF]
, 2019 BackgroundCharacterization of the skin and wound microbiome is of high biomedical interest, but is hampered by the low biomass of typical samples. While sample preparation from other microbiomes (e.g., gut) has been the subject of extensive optimization,
Chen, Irene A +3 more
core +1 more source
In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus. [PDF]
, 2016 Packaging of the genome into a protein capsid and its subsequent delivery into a host cell are two fundamental processes in the life cycle of a virus. Unlike double-stranded DNA viruses, which pump their genome into a preformed capsid, single-stranded ...
Dai, Xinghong +6 more
core +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Frontiers in MicrobiologyPhages are ubiquitous and diverse, playing a key role in maintaining microbial ecosystem balance. However, their diversity, potential applications, and their interactions with hosts and other phages remain largely unexplored.
Chao Wei, Zhe Chen
doaj +1 more source
Role of the host cell in bacteriophage T4 development. II. Characterization of host mutants that have pleiotropic effects on T4 growth [PDF]
, 1980 Mutant host-defective Escherichi coli that fail to propagate bacteriophage T4 and have a pleiotropic effect on T4 development have been isolated and characterized.
Lielausis, Ilga +3 more
core
Making serine integrases work for us [PDF]
, 2017 DNA site-specific recombinases are enzymes (often associated with mobile DNA elements) that catalyse breaking and rejoining of DNA strands at specific points, thereby bringing about precise genetic rearrangements.
Stark, W. Marshall
core +1 more source
A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats
Advanced Science, EarlyView.ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang +13 more
wiley +1 more source
Isolation and genomic analysis of phage BUCT551 against drug-resistant Aeromonas hydrophila
Frontiers in Veterinary ScienceAeromonas hydrophila (A. hydrophila) is a common pathogen in aquaculture that also causes opportunistic infections and sporadic food- and water-borne illness in humans.
Pengjun Han +6 more
doaj +1 more source
Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy
Advanced Science, EarlyView.Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao +12 more
wiley +1 more source