Results 111 to 120 of about 126,149 (256)

RNA viral protein structure database: A comprehensive and user‐friendly web database for RNA viral protein structures

iMetaOmics, EarlyView.
Given the central role of protein structures in RNA virus biology, the RNA viral protein structure database (RVPSD, https://virus.9itsg.net) integrates taxonomic classification, viral nucleotide and protein sequences, functional annotations, and predicted three‐dimensional protein structures.
Qiangzhen Yang, Zhongshuai Tian, Tao Hu, Jiangrong Lou, Hengcong Liu, Edward C. Holmes, Yongyong Shi, Juan Li, Weifeng Shi   +8 more
wiley   +1 more source

Genomic analysis and characterization of lytic bacteriophages that target antimicrobial resistant Escherichia coli in Addis Ababa, Ethiopia

Heliyon
The emergence of antibiotic resistance in E. coli strains has sparked a fervent investigation of alternative therapies, such as the use of lytic bacteriophages.
Tamirat Salile Sada, Dawit Hailu Alemayehu, Kalkidan Melaku Tafese, Tesfaye Sisay Tessema   +3 more
doaj   +1 more source

The genome and proteome of a virulent Escherichia coli O157:H7 bacteriophage closely resembling Salmonella phage Felix O1

Virology Journal, 2009
Based upon whole genome and proteome analysis, Escherichia coli O157:H7-specific bacteriophage (phage) wV8 belongs to the new myoviral genus, "the Felix O1-like viruses" along with Salmonella phage Felix O1 and Erwinia amylovora phage φEa21-4. The genome
Waddell Thomas E, Ackermann Hans-Wolfgang, Ojha Shivani, Mazzocco Amanda, Lingohr Erika J, Kropinski Andrew M, She Yi-Min, Villegas Andre, Moyles Dianne M, Ahmed Rafiq, Johnson Roger P   +10 more
doaj   +1 more source

PhaGAA: an integrated web server platform for phage genome annotation and analysis. [PDF]

Bioinformatics, 2023
Wu J, Liu Q, Li M, Xu J, Wang C, Zhang J, Xiao M, Bin Y, Xia J.   +8 more
europepmc   +1 more source

Viruses in the sediments around the trenches harbor diverse survival mechanisms

iMetaOmics, EarlyView.
Deep‐sea trenches are the deepest and most isolated environments in the global ocean but the diversity and adaptation of the viral communities remain poorly characterized. In this study, 5563 viral operational taxonomic units (vOTUs) were identified from sediments of the Yap Trench and Western Caroline Basin.
Yue Su, Hao Yu, Shujuan Sun, Kaiyang Zheng, Ziyue Wang, Chen Gao, Guangxue Li, Xiaoshou Liu, Hongbing Shao, David Paez‐Espino, Andrew McMinn, Yantao Liang, Min Wang   +12 more
wiley   +1 more source

Broad-spectrum CRISPR-Cas13a enables efficient phage genome editing. [PDF]

Nat Microbiol, 2022
Adler BA, Hessler T, Cress BF, Lahiri A, Mutalik VK, Barrangou R, Banfield J, Doudna JA.   +7 more
europepmc   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Complete genome sequence of the novel virulent phage PMBT24 infecting Enterocloster bolteae from the human gut

Heliyon
PMBT24, the first reported virulent bacteriophage infecting the anaerobic human gut bacterium Enterocloster bolteae strain MBT-21, was isolated from a municipal sewage sample and its genome was sequenced and analysed.
Sabrina Sprotte, Erik Brinks, Horst Neve, Charles M.A.P. Franz   +3 more
doaj   +1 more source

Phage Genome Diversity in a Biogas-Producing Microbiome Analyzed by Illumina and Nanopore GridION Sequencing. [PDF]

Microorganisms, 2022
Willenbücher K, Wibberg D, Huang L, Conrady M, Ramm P, Gätcke J, Busche T, Brandt C, Szewzyk U, Schlüter A, Barrero Canosa J, Maus I.   +11 more
europepmc   +1 more source