Results 131 to 140 of about 125,595 (262)

SIB1‐SEC23A undergo ER to chloroplast relocalization to mediate immunity in Arabidopsis thaliana

Journal of Integrative Plant Biology, EarlyView.
SEC23A mediates membrane trafficking between the endoplasmic reticulum (ER) and Golgi apparatus and interacts with the immunity protein SIGMA FACTOR‐BINDING PROTEIN1 in Arabidopsis. Under stress, both proteins relocate from the ER to chloroplasts, suppressing photosynthesis genes and enhancing defense genes.
Jialin Peng, Huan Zhong, Jianan Zhang, Hailei Zhang, Wuzhen Liu, Yonglun Zeng, Liwen Jiang, Yiji Xia   +7 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Isolation of a Novel Lytic Pseudomonas aeruginosa Phage Henu5 and Fitness Costs of Phage-Driven Resistance. [PDF]

Microb Biotechnol
This study isolated and identified a novel lytic phage that infects Pseudomonas aeruginosa. Henu5 exhibited good physicochemical stability. Additionally, the phage‐resistant mutants showed fitness trade‐offs in growth, virulence and antibiotic susceptibility, along with in vivo fitness, which might direct future phage selection in clinical settings ...
Gomaa SE, Shen J, Li J, Liu Y, Ma C, Li Q, Qi G, Teng T.   +7 more
europepmc   +2 more sources

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Elucidation of molecular function of phage protein responsible for optimization of host cell lysis

BMC Microbiology
Background Bacteriophages (or phages) replicate by utilizing bacterial resources and destroy their host cells at the end of the replication cycle. Phages employ multiple proteins to optimize host cell lysis, thereby maximizing the production of phage ...
Jinwoo Kim, Joonbeom Kim, Sangryeol Ryu
doaj   +1 more source

In Salmonella Typhimurium, YiiD Modulates cAMP Levels in Lag Phase During Growth on Succinate

Molecular Microbiology, EarlyView.
The YiiD enzyme, found by others to perform a redundant role in fatty acid biosynthesis, is found to be unexpectedly required for the early increase in cAMP in lag phase during growth on succinate. This intriguing finding suggests a mechanistic link may exist between fatty acid biosynthesis and catabolite repression. ABSTRACT In Salmonella Typhimurium (
John A. Ciemniecki, Jessica L. Will, Jorge C. Escalante‐Semerena   +2 more
wiley   +1 more source

Ultraconserved bacteriophage genome sequence identified in 1300-year-old human palaeofaeces

Nature Communications
Bacteriophages are widely recognised as rapidly evolving biological entities. However, knowledge about ancient bacteriophages is limited. Here, we analyse DNA sequence datasets previously generated from ancient palaeofaeces and human gut-content samples,
Piotr Rozwalak, Jakub Barylski, Yasas Wijesekara, Bas E. Dutilh, Andrzej Zielezinski   +4 more
doaj   +1 more source

Galaxy and Apollo as a biologist-friendly interface for high-quality cooperative phage genome annotation. [PDF]

PLoS Comput Biol, 2020
Ramsey J, Rasche H, Maughmer C, Criscione A, Mijalis E, Liu M, Hu JC, Young R, Gill JJ.   +8 more
europepmc   +1 more source

Regulation of the Yersinia pseudotuberculosis Type III Secretion System by the CpxAR Two‐Component System

Molecular Microbiology, EarlyView.
Host tissue cues including temperature, oxygen, and iron availability regulate expression of the Yersinia type III secretion system (T3SS) master regulator LcrF. We found that CpxR inhibits LcrF through an indirect, multi‐factorial mechanism and identified the osmolarity‐sensing OmpR/EnvZ system as an additional regulator of LcrF, highlighting ...
Karen Hug, Erin Mettert, Melissa Estrada Escobar, Cristina Vargas Vazquez, David Balderas, Sarvind Tripathi, Laya Ashley, Patricia J. Kiley, Victoria Auerbuch   +8 more
wiley   +1 more source

First crAss-Like Phage Genome Encoding the Diversity-Generating Retroelement (DGR). [PDF]

Viruses, 2020
Morozova V, Fofanov M, Tikunova N, Babkin I, Morozov VV, Tikunov A.   +5 more
europepmc   +1 more source