Results 151 to 160 of about 992,387 (299)

Complete genome sequence of the Escherichia coli phage Ayreon

, 2018
We report the whole-genome sequence of a new Escherichia coli temperate phage, Ayreon, comprising a linear double-stranded DNA (dsDNA) genome of 44,708 ...
Vlot, Marnix, Franklin L. Nobrega, Wong, Che F. A., Brouns, Stan JJ, Liu, Yue (author), Marnix Vlot, Brouns, Stan J.J., Luzia de Nobrega, F. (author), Nobrega, Franklin L., Yue Liu, Stan J. J. Brouns, Wong, Che F.A., Brouns, S.J.J. (author), Brouns, S.J.J., Che F. A. Wong, Luzia De Nobrega, Franklin, Liu, Yue, Wong, Che F.A. (author), Luzia de Nobrega, F., Vlot, Marnix (author)   +19 more
core   +2 more sources

Induction and Enhancement of Bacteriocin Production (Review)

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Conventionally, bacteriocins are produced by microorganisms on complex substrates, released as semi‐purified preparations or crude fermentates. These bacteriocin‐containing products often exhibit unsatisfactory purity, low active‐substance content, and high production costs, limiting their commercialization and use. This review aims to analyze
Oksana Knysh, Artur Martynov
wiley   +1 more source

Genomic and Phenotypic Characterization of Two Novel Enterobacter Phages With EDTA-Enhanced Antibiofilm Activity. [PDF]

Microbiologyopen
Two novel lytic Enterobacter phages, HHH and RZH, displayed targeted antibiofilm activity against MDR Enterobacter cloacae complex biofilms when combined with EDTA. Activity was strongest within a narrow low‐millimolar EDTA window, reducing biofilm biomass and viable burden, while higher EDTA concentrations shifted the interaction towards antagonism ...
Haq K, Newland-Smith Z, Figgit M, Lee D, Duedu K.   +4 more
europepmc   +2 more sources

Autonomous Control of Gene Expression Using Endogenous Transcription Signals

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Autonomous cell‐based control of heterologous gene expression can simplify batch‐culture bioprocessing by eliminating external monitoring and extrinsic control of culture conditions. Existing approaches use auto‐induction media, synthetic cell‐cell communication systems, or application‐specific biosensors.
Pakpoom Subsoontorn, Drew Endy, Olivier Borkowski   +2 more
wiley   +1 more source

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

BMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu, Aohan Luan, Yujun Yang, Linlin Wang, Huilin Wang, Ning Wang, Guixin He, Yajie Yang, Rabiya Noor, Jawad Hussain, Longquan Shao   +10 more
wiley   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Continental scale metagenomics reveals Microcystis‐induced synchrony among aquatic taxa is exacerbated by trophic cascades

Ecography, EarlyView.
Harmful Microcystis proliferation severely threatens aquatic ecosystems globally, but its impacts on food‐web stability remain poorly understood. Here, we analyzed 1309 metagenomic samples from freshwater ecosystems across China to investigate how Microcystis abundance affects synchrony among taxa in multi‐trophic food webs (from bacteriophages to ...
Lemian Liu, Siqi Zhu, Xiaoqin Huang, Wenjia Hu, Lixiang Luo, Xiusong Pan, Jianfeng Chen   +6 more
wiley   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Genetic basis of phage-host interaction: Towards effective phage therapy of non-typhoidal Salmonella

, 2022
Non-typhoidal Salmonella (NTS) have adapted to cause invasive illness in humans. Bacteria have developed MDR against current antibiotics. Bacteriophage therapy is the hope for bacterial treatment however one of the key limitations is the limited host ...
Mohammed, M.
core   +1 more source

Genome map of phage HY01.

, 2016
Genome map of phage HY01.
Dong-Hoon Lee (106435), Heyn Lee (3609098), Hye-Jin Ku (3539804), Sangryeol Ryu (12777), Ju-Hoon Lee (50046), You-Tae Kim (3539795), Hakdong Shin (140710)   +6 more
core   +1 more source