Results 161 to 170 of about 1,053,752 (301)

Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM. [PDF]

Structure, 2021
Shen BW, Quispe JD, Luyten Y, McGough BE, Morgan RD, Stoddard BL.   +5 more
europepmc   +1 more source

The complete genome sequence of Escherichia phage SRT7, a novelT7?like phage

, 2019
In this study, we isolated a novel virulent Escherichia phage, SRT7. Its genome is a double-stranded linear DNA moleculecontaining 39,883 bp. Direct terminal repeats with a length of 175 bp, are present at both ends of the genome. The G+Ccontent is 50.54%
Zhao, Kaili...[et al.]
core  

Genome Sequence of Escherichia coli Tailed Phage Utah

, 2017
Escherichia coli bacteriophage Utah is a member of the chi-like tailed phage cluster in the Siphoviridae family. We report here the complete 59,024-bp sequence of the genome of phage Utah.
Ananda S. Bhattacharjee, Eddie B. Gilcrease, Sherwood R. Casjens, Alexandra J. Heitkamp, Justin C. Leavitt   +4 more
core   +1 more source

DNA Nanotechnology Meets Peptide and Protein Self‐Assembly

Chemistry – A European Journal, EarlyView.
Combining DNA nanotechnology with peptide and protein assembly provides complementary platforms for the rational engineering of functional biomaterials. This Perspective discusses the emerging field of self‐assembling DNA‐peptide and DNA‐protein hybrid systems that combine the structural precision and programmability of DNA nanotechnology with the ...
Marcel Hanke, Nanjundan Raghul, Adrian Keller, Veikko Linko, Verónica I. Dodero   +4 more
wiley   +1 more source

Engineering Mosaic T7 Bacteriophages for Dual Peptide Display to Enable Cellular Targeting and Ligand-Directed Protein Capture. [PDF]

Biotechnol J
Graphical Abstract and Lay Summary A mosaic T7 phage platform enables simultaneous display of two independent peptides on the same phage particle. The modular design integrates receptor targeting, protein capture, and tissue‐directed in vivo phage display, establishing a versatile methodology for multifunctional phage engineering, receptor ...
Marchetti L, Põšnograjeva K, Lingasamy P, Pleiko K, Ilves I, Teesalu T.   +5 more
europepmc   +2 more sources

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Jumbo phage-mediated transduction of genomic islands

Proceedings of the National Academy of Sciences
Abstract Bacteria acquire new genes by horizontal gene transfer (HGT), typically mediated by mobile genetic elements (MGEs). While plasmids, bacteriophages and certain integrative and conjugative elements (ICEs) are well characterized, the broader diversity of MGEs remains poorly understood.
Yansong Zhao, Yue Ma, Christina Vasileiou, Andrew D. Farr, David W. Rogers, Paul B. Rainey   +5 more
openaire   +5 more sources

crAss-like phage genome and protein sequences

, 2019
Updated 15/01/2019:249 crAss-like phage contigs detected in metagenomic sequencing data of human faecal virome/phageome studies.Includes prodigal protein predictions of genome sequences, with candidate genus 7 and 8 predictions performed using genetic ...
Stephen Stockdale (5063873)
core   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

FlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu, Yubing Hu, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

Isolation and genomic characterization of a lytic bacteriophage against multidrug-resistant Proteus mirabilis

Applied Microbiology and Biotechnology
Multidrug-resistant (MDR) Proteus mirabilis is a significant opportunistic pathogen, largely due to its ability to form robust biofilms that are recalcitrant to conventional antibiotic therapy.
Parmanand Kushwaha, Sovon Acharya, Manisha Behera, Shailesh Desai, Surajit Gandhi, Munindra Ruwali, Lakshminarasimhan Krishnaswamy, Sarika Chaturvedi, Sachinandan De, Prashanth Suravajhala, Gyaneshwer Chaubey   +10 more
doaj   +1 more source