Results 11 to 20 of about 190,753 (310)

Phage diversity, genomics and phylogeny [PDF]

Nature Reviews Microbiology, 2020
Recent advances in viral metagenomics have enabled the rapid discovery of an unprecedented catalogue of phages in numerous environments, from the human gut to the deep ocean. Although these advances have expanded our understanding of phage genomic diversity, they also revealed that we have only scratched the surface in the discovery of novel viruses ...
Frank Oechslin, Sylvain Moineau
exaly   +3 more sources

Continuous multiplexed phage genome editing using recombitrons. [PDF]

Nat Biotechnol
Bacteriophage genome editing can enhance the efficacy of phages to eliminate pathogenic bacteria in patients and in the environment. However, current methods for editing phage genomes require laborious screening, counterselection or in vitro construction of modified genomes.
Fishman CB, Crawford KD, Bhattarai-Kline S, Poola D, Zhang K, González-Delgado A, Rojas-Montero M, Shipman SL.   +7 more
europepmc   +3 more sources

Genome Structure of Caulobacter Phage phiCb5 [PDF]

Journal of Virology, 2011
ABSTRACT The complete genome sequence of caulobacter phage phiCb5 has been determined, and four open reading frames (ORFs) have been identified and characterized. As for related phages, the ORFs code for maturation, coat, replicase, and lysis proteins, but unlike other Leviviridae members, the lysis ...
Andris, Kazaks, Tatyana, Voronkova, Janis, Rumnieks, Andris, Dishlers, Kaspars, Tars   +4 more
openaire   +2 more sources

A Roadmap for Genome-Based Phage Taxonomy [PDF]

Viruses, 2021
Bacteriophage (phage) taxonomy has been in flux since its inception over four decades ago. Genome sequencing has put pressure on the classification system and recent years have seen significant changes to phage taxonomy. Here, we reflect on the state of phage taxonomy and provide a roadmap for the future, including the abolition of the order ...
Dann Turner, Andrew M. Kropinski, Evelien M. Adriaenssens   +2 more
openaire   +3 more sources

Genome Sequence of Mycobacterium Phage CrystalP [PDF]

Genome Announcements, 2017
ABSTRACT Mycobacteriophage CrystalP is a newly isolated phage infecting Mycobacterium smegmatis strain mc 2 155. CrystalP has a 76,483-bp genome and is predicted to contain 143 protein-coding and 2 tRNA genes, including repressor and integrase genes consistent with a temperate ...
Christine L. Fleischacker, Miriam Segura-Totten, Rebecca A. Garlena, Deborah Jacobs-Sera, Welkin H. Pope, Daniel A. Russell, Graham F. Hatfull, David Asai, Suparna Bhalla, Billy Biederman, Rebecca Bortz, Timothy Breton, Chris Brey, Victoria Brown-Kennerly, Kristen Butela, Brad Cavinder, Bernadette Connors, Steven Cresawn, Jillian Decker, Kristen Delaney Nguyen, Arturo Diaz, Madeline Dojs, Jean Doty, Dale Edwards, Kayla Fast, Christine Fleischacker, Victoria Frost, Laurie Furlong, Eid Haddad, Graham Hatfull, Lee Hughes, Debbie Jacobs-Sera, Joanna Katsanos, Evan Kesinger, Bridgette Kirkpatrick, Priscilla Kobi, Ann Koga, Jonathan Lawson, Stephanie Martin, Jeff McLean, Evan Merkhofer, Jacob Montgomery, Etsuko Moriyama, Margaret Nordlie Gibson, Manuel Ospina-Giraldo, Carleitta Paige-Anderson, Welkin Pope, Ann Powell, Mary Preuss, Vernon Ruffin, Dan Russell, Michael Sandel, Anne Scherer, J. Schwebach, Melody Scrudato, M. Esa Seegulam, Miriam Segura-Totten, Vic Sivanathan, Mary Ann Smith, Joyce Stamm, Nate Sutter, Sara Tolsma, Carole Twichell, Ana Maria Valle-Rivera, Tony Washington, Scott Weir, Kristi Westover, Wenbo Yan   +67 more
openaire   +2 more sources

Genome Characterization of Gordonia Phage Amore2

Microbiology Resource Announcements, 2022
Novel Gordonia phage Amore2 was isolated from Pittsburgh, Pennsylvania and infects Gordonia terrae 3612. Amore2 was placed into Actinobacteria cluster CS1. Its genome is 73,842 bp with 105 predicted open reading frames and 56.6% GC content.
Caroline M. Lantis, Emily C. Mattison, Sarah E. Miller, Alexandria J. Williams, Alison E. Kanak   +4 more
openaire   +2 more sources

Mobile effector proteins on phage genomes [PDF]

Bacteriophage, 2012
Bacteriophage genomes found in a range of bacterial pathogens encode a diverse array of virulence factors ranging from superantigens or pore forming lysins to numerous exotoxins. Recent studies have uncovered an entirely new class of bacterial virulence factors, called effector proteins or effector toxins, which are encoded within phage genomes that ...
Boyd, E. Fidelma, Carpenter, Megan R., Chowdhury, Nityananda   +2 more
openaire   +2 more sources

Characterizing Phage Genomes for Therapeutic Applications [PDF]

Viruses, 2018
Multi-drug resistance is increasing at alarming rates. The efficacy of phage therapy, treating bacterial infections with bacteriophages alone or in combination with traditional antibiotics, has been demonstrated in emergency cases in the United States and in other countries, however remains to be approved for wide-spread use in the US.
Casandra Philipson, Logan Voegtly, Matthew Lueder, Kyle Long, Gregory Rice, Kenneth Frey, Biswajit Biswas, Regina Cer, Theron Hamilton, Kimberly Bishop-Lilly   +9 more
openaire   +3 more sources

Genome Sequence of Arthrobacter Phage NathanVaag

Microbiology Resource Announcements, 2022
We report the genome sequence of bacteriophage NathanVaag, an actinobacteriophage isolated from soil in El Paso, Texas, that infects Arthrobacter sp. strain ATCC 21022. The 49,645-bp genome contains 73 predicted protein-coding genes.
Rebecca A. Chong, Charlie M. Cosse, Viviana Gaytan, Dylan S. Green, Cade J. Kane, Kirsten A. Kasal, Zarek K. Kon, Rosa E. Maxwell, Vlas Olaru, Tuan D. Pham, MeiLin F. Precourt, Joseph R. Romero, Wellington J. Rothschild, Shantelle N. Sales, Troy D. Sensano, Wesley E. Simko, Inugiksuq J. Smith, Mika A. Toor, Adelaide R. Wilson, Megan L. Porter   +19 more
openaire   +2 more sources

Soil Giant Phage: Genome and Biological Characteristics of Sinorhizobium Jumbo Phage. [PDF]

Int J Mol Sci
This paper presents the first in-depth research on the biological and genomic properties of lytic rhizobiophage AP-J-162 isolated from the soils of the mountainous region of Dagestan (North Caucasus), which belongs to the centers of origin of cultivated plants, according to Vavilov N.I. The rhizobiophage host strains are nitrogen-fixing bacteria of the
Kozlova AP, Muntyan VS, Vladimirova ME, Saksaganskaia AS, Kabilov MR, Gorbunova MK, Gorshkov AN, Grudinin MP, Simarov BV, Roumiantseva ML.   +9 more
europepmc   +3 more sources