Results 11 to 20 of about 125,595 (262)

Phage diversity, genomics and phylogeny [PDF]

Nature Reviews Microbiology, 2020
Recent advances in viral metagenomics have enabled the rapid discovery of an unprecedented catalogue of phages in numerous environments, from the human gut to the deep ocean. Although these advances have expanded our understanding of phage genomic diversity, they also revealed that we have only scratched the surface in the discovery of novel viruses ...
Moïra B. Dion, Frank Oechslin, Sylvain Moineau   +2 more
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The Caulobacter crescentus phage phiCbK: genomics of a canonical phage [PDF]

BMC Genomics, 2012
AbstractBackgroundThe bacteriumCaulobacter crescentusis a popular model for the study of cell cycle regulation and senescence. The large prolate siphophage phiCbK has been an important tool inC. crescentusbiology, and has been studied in its own right as a model for viral morphogenesis.
Gill Jason J, Berry Joel D, Russell William K, Lessor Lauren, Escobar-Garcia Diego A, Hernandez Daniel, Kane Ashley, Keene Jennifer, Maddox Matthew, Martin Rebecca, Mohan Sheba, Thorn Ashlyn M, Russell David H, Young Ry   +13 more
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The Phage Proteomic Tree: a Genome-Based Taxonomy for Phage [PDF]

Journal of Bacteriology, 2002
ABSTRACTThere are ∼1031phage in the biosphere, making them the most abundant biological entities on the planet. Despite their great numbers and ubiquitous presence, very little is known about phage biodiversity, biogeography, or phylogeny. Information is limited, in part, because the current ICTV taxonomical system is based on culturing phage and ...
Forest, Rohwer, Rob, Edwards
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Marine phage genomics: the tip of the iceberg [PDF]

FEMS Microbiology Letters, 2016
Marine viruses are the most abundant biological entity in the oceans, the majority of which infect bacteria and are known as bacteriophages. Yet, the bulk of bacteriophages form part of the vast uncultured dark matter of the microbial biosphere. In spite of the paucity of cultured marine bacteriophages, it is known that marine bacteriophages have major
Perez-Sepulveda, Blanca, Redgwell, Tamsin, Rihtman, Branko, Pitt, Frances Diana, Scanlan, David J. , Millard, Andrew D., Hantke, Klaus   +6 more
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The Genome of the Novel Phage Rtp, with a Rosette-Like Tail Tip, IsHomologous to the Genome of Phage T1 [PDF]

Journal of Bacteriology, 2006
ABSTRACTAnewEscherichia coliphage, named Rtp, was isolated and shown to be closely related to phage T1. Electron microscopy revealed that phage Rtp has a morphologically unique tail tip consisting of four leaf-like structures arranged in a rosette, whereas phage T1 has thinner, flexible leaves that thicken toward the ends.
Wietzorrek, A., Schwarz, H., Herrmann, C., Braun, V. ; https://orcid.org/0000-0003-0093-8595   +3 more
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Genome Structure of Caulobacter Phage phiCb5 [PDF]

Journal of Virology, 2011
ABSTRACT The complete genome sequence of caulobacter phage phiCb5 has been determined, and four open reading frames (ORFs) have been identified and characterized. As for related phages, the ORFs code for maturation, coat, replicase, and lysis proteins, but unlike other Leviviridae members, the lysis ...
Andris, Kazaks, Tatyana, Voronkova, Janis, Rumnieks, Andris, Dishlers, Kaspars, Tars   +4 more
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CRISPR Immunity Drives Rapid Phage Genome Evolution in Streptococcus thermophilus

mBio, 2015
Many bacteria rely on CRISPR-Cas systems to provide adaptive immunity against phages, predation by which can shape the ecology and functioning of microbial communities.
David Paez-Espino, Itai Sharon, Wesley Morovic, Buffy Stahl, Brian C. Thomas, Rodolphe Barrangou, Jillian F. Banfield   +6 more
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Sequencing and Characterization of Pseudomonas aeruginosa phage JG004

BMC Microbiology, 2011
Background Phages could be an important alternative to antibiotics, especially for treatment of multiresistant bacteria as e.g. Pseudomonas aeruginosa.
Bunk Boyke, Garbe Julia, Rohde Manfred, Schobert Max   +3 more
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What does the talking?: quorum sensing signalling genes discovered in a bacteriophage genome. [PDF]

PLoS ONE, 2014
The transfer of novel genetic material into the genomes of bacterial viruses (phages) has been widely documented in several host-phage systems. Bacterial genes are incorporated into the phage genome and, if retained, subsequently evolve within them.
Katherine R Hargreaves, Andrew M Kropinski, Martha R J Clokie   +2 more
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Characterizing Phage Genomes for Therapeutic Applications [PDF]

Viruses, 2018
Multi-drug resistance is increasing at alarming rates. The efficacy of phage therapy, treating bacterial infections with bacteriophages alone or in combination with traditional antibiotics, has been demonstrated in emergency cases in the United States and in other countries, however remains to be approved for wide-spread use in the US.
Casandra Philipson, Logan Voegtly, Matthew Lueder, Kyle Long, Gregory Rice, Kenneth Frey, Biswajit Biswas, Regina Cer, Theron Hamilton, Kimberly Bishop-Lilly   +9 more
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