Articles selected by Faculty of 1000: ectopic gene conversions; heterozygous insertions in C. elegans; plant RNA silencing suppression; phage insertion into the host genome; screening viral protein variants [PDF]
, 2005 openalex +1 more source
Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Accurate biomolecular structure prediction enables the prediction of mutational effects, the speculation of function based on predicted structural homology, the analysis of ligand binding modes, experimental model building, and many other applications.
Rachael C. Kretsch +32 more
wiley +1 more source
Galaxy and Apollo as a biologist-friendly interface for high-quality cooperative phage genome annotation. [PDF]
PLoS Comput Biol, 2020 Ramsey J +8 more
europepmc +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
Small, EarlyView.The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
Phage lambda genome concatemerization v1 [PDF]
, 2019 This protocol is used to create concatemers of phage genomes. This is done by ligating phage lambda genomes using the overhangs at the cos site with T4 ligase.
openaire +2 more sources
First crAss-Like Phage Genome Encoding the Diversity-Generating Retroelement (DGR). [PDF]
Viruses, 2020 Morozova V +5 more
europepmc +1 more source
The Genome and Structural Proteome of YuA, a New Pseudomonas aeruginosa Phage Resembling M6 [PDF]
, 2007 Pieter‐Jan Ceyssens +10 more
openalex +1 more source
Understanding of endo/lysosomal escape of nanomaterials in biomedical application
Smart Molecules, EarlyView.This review summarized mainstream mechanisms of endo/lysosomal escape and design strategies of endo/lysosomal escapable nanoparticles in view of surface charge, polarity & hydrophobicity, particle morphology, and lysosomal escape agents. The utilization of endo/lysosomal escapable nanoparticles for vaccine delivery and genetic engineering are ...
Xin Wang +3 more
wiley +1 more source
Quantitative Study of the Chiral Organization of the Phage Genome Induced by the Packaging Motor. [PDF]
Biophys J, 2020 Cruz B +4 more
europepmc +1 more source