Phage Therapy-Challenges, Opportunities and Future Prospects. [PDF]
Pharmaceuticals (Basel), 2023 The increasing drug resistance of bacteria to commonly used antibiotics creates the need to search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly.
Zalewska-Piątek B.
europepmc +2 more sources
A Comprehensive Review on Phage Therapy and Phage-Based Drug Development. [PDF]
Antibiotics (Basel)Phage therapy, the use of bacteriophages (phages) to treat bacterial infections, is regaining momentum as a promising weapon against the rising threat of multidrug-resistant (MDR) bacteria.
Cui L +10 more
europepmc +2 more sources
Recent Progress in Phage Therapy to Modulate Multidrug-Resistant Acinetobacter baumannii, Including in Human and Poultry [PDF]
Antibiotics, 2022 Acinetobacter baumannii is a multidrug-resistant and invasive pathogen associated with the etiopathology of both an increasing number of nosocomial infections and is of relevance to poultry production systems.
Chui, Wenting +14 more
core +2 more sources
Improving phage therapy by evasion of phage resistance mechanisms. [PDF]
JAC Antimicrob Resist, 2023 Antibiotic failure is one of the most worrisome threats to global health. Among the new therapeutic efforts that are being explored, the use of bacteriophages (viruses that kill bacteria), also known as ‘phages’, is being extensively studied as a ...
Bleriot I +10 more
europepmc +2 more sources
The Future of Clinical Phage Therapy in the United Kingdom
Viruses, 2023 Bacteriophage (phage) therapy is a promising alternative antimicrobial strategy with the potential to transform the way bacterial infections are treated. In the United Kingdom, phages are classed as a biological medicine.
Joshua D. Jones +4 more
doaj +2 more sources
Perception of phage therapy and research across selected professional and social groups in Poland [PDF]
Frontiers in Public HealthThere is no doubt that in the last 15 years phage therapy has re-emerged from the shadow of antibiotics, from the perspective of both scientists and various patient advocacy groups.
Maciej Żaczek +8 more
doaj +2 more sources
Current challenges and future opportunities of phage therapy [PDF]
FEMS Microbiology Reviews, 2020 Antibiotic resistance is a major public health challenge worldwide, whose implications for global health might be devastating if novel antibacterial strategies are not quickly developed.
Diana P. Pires +4 more
openalex +2 more sources
Efficacy of systemic temozolomide‐activated phage‐targeted gene therapy in human glioblastoma
EMBO Molecular Medicine, 2019 Glioblastoma multiforme (GBM) is the most lethal primary intracranial malignant neoplasm in adults and most resistant to treatment. Integration of gene therapy and chemotherapy, chemovirotherapy, has the potential to improve treatment. We have introduced
Justyna Magdalena Przystal +12 more
doaj +2 more sources
Mapping the tail fiber as the receptor binding protein responsible for differential host specificity of Pseudomonas aeruginosa bacteriophages PaP1 and JG004. [PDF]
, 2013 The first step in bacteriophage infection is recognition and binding to the host receptor, which is mediated by the phage receptor binding protein (RBP). Different RBPs can lead to differential host specificity.
He, Xuesong +7 more
core +27 more sources
Frontiers in Pharmacology, 2021 Background: Chronic Bacterial Prostatitis (CBP) is an inflammatory condition caused by a persistent bacterial infection of the prostate gland and its surrounding areas in the male pelvic region. It is most common in men under 50 years of age.
Apurva Virmani Johri +5 more
doaj +1 more source