Results 121 to 130 of about 4,514,314 (397)

Characterization, antibacterial, and cytotoxic activities of silver nanoparticles using the whole biofilm layer as a macromolecule in biosynthesis

open access: yesScientific Reports
Recently, multi-drug resistant (MDR) bacteria are responsible for a large number of infectious diseases that can be life-threatening. Globally, new approaches are targeted to solve this essential issue.
Aghapy Yermans Yakoup   +4 more
doaj   +1 more source

Efficacy Assessment of Phage Therapy in Treating Staphylococcus aureus-Induced Mastitis in Mice

open access: yesViruses, 2022
The primary aim of this study was to evaluate the efficacy of phage against mastitis induced by drug-resistant S. aureus in a mouse model. In this study, five S.
Feixiang Teng   +14 more
semanticscholar   +1 more source

Phages and phage therapy: past, present and future

open access: yesMicrobiologia Medica, 2020
Bacteriophages are viruses that infect bacteria. Since their discovery in the last century, they have proved their effectiveness in biocontrol of bacteria. In this mini-review, we provide a brief history of bacteriophages, their life cycle and classification.
Martina Rossitto   +2 more
openaire   +3 more sources

Bacteriophage Mediates Efficient Gene Transfer in Combination with Conventional Transfection Reagents

open access: yesViruses, 2015
The development of commercially available transfection reagents for gene transfer applications has revolutionized the field of molecular biology and scientific research.
Amanda Donnelly   +4 more
doaj   +1 more source

Well-temperate phage: optimal bet-hedging against local environmental collapses [PDF]

open access: yesScientific Reports 5, Article number: 10523 (2015), 2013
Upon infection of their bacterial hosts temperate phages must chose between lysogenic and lytic developmental strategies. Here we apply the game-theoretic bet-hedging strategy introduced by Kelly to derive the optimal lysogenic fraction of the total population of phages as a function of frequency and intensity of environmental downturns affecting the ...
arxiv   +1 more source

Phage therapy of pulmonary infections [PDF]

open access: yesBacteriophage, 2015
It is generally agreed that a bacteriophage-associated phenomenon was first unambiguously observed one-hundred years ago with the findings of Twort in 1915. This was independently followed by complementary observations by d'Hérelle in 1917. D'Hérelle's appreciation of the bacteriophage phenomenon appears to have directly led to the development of ...
openaire   +3 more sources

Mimicking Biochemical Traits with a Synthetic Lipid Nanoparticles SARS‐COV‐2 Model

open access: yesAdvanced Therapeutics, EarlyView.
A synthetic virus model developed using lipid nanoparticles, which incorporate encapsulated mRNA and nucleocapsid (N) protein along with surface‐conjugated spike (S) protein, mimics the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), allowing for the advancement of diagnostic product assessment.
Ignasia Handipta Mahardika   +7 more
wiley   +1 more source

Phascinating Phages

open access: yesMicroorganisms, 2022
Treatment of infections caused by bacteria has become more complex due to the increasing number of bacterial strains that are resistant to conventional antimicrobial therapy.
Marek Straka   +2 more
doaj   +1 more source

Phages and human health: More than idle hitchhikers [PDF]

open access: yes, 2019
Bacteriophages, or phages, are viruses that infect bacteria and archaea. Phages have diverse morphologies and can be coded in DNA or RNA and as single or double strands with a large range of genome sizes. With the increasing use of metagenomic sequencing
Baldridge, Megan T   +2 more
core   +2 more sources

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

open access: yesAdvanced Science, EarlyView.
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang   +4 more
wiley   +1 more source

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