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Recently, multi-drug resistant (MDR) bacteria are responsible for a large number of infectious diseases that can be life-threatening. Globally, new approaches are targeted to solve this essential issue.
Aghapy Yermans Yakoup+4 more
doaj +1 more source
Efficacy Assessment of Phage Therapy in Treating Staphylococcus aureus-Induced Mastitis in Mice
The primary aim of this study was to evaluate the efficacy of phage against mastitis induced by drug-resistant S. aureus in a mouse model. In this study, five S.
Feixiang Teng+14 more
semanticscholar +1 more source
Phages and phage therapy: past, present and future
Bacteriophages are viruses that infect bacteria. Since their discovery in the last century, they have proved their effectiveness in biocontrol of bacteria. In this mini-review, we provide a brief history of bacteriophages, their life cycle and classification.
Martina Rossitto+2 more
openaire +3 more sources
The development of commercially available transfection reagents for gene transfer applications has revolutionized the field of molecular biology and scientific research.
Amanda Donnelly+4 more
doaj +1 more source
Well-temperate phage: optimal bet-hedging against local environmental collapses [PDF]
Upon infection of their bacterial hosts temperate phages must chose between lysogenic and lytic developmental strategies. Here we apply the game-theoretic bet-hedging strategy introduced by Kelly to derive the optimal lysogenic fraction of the total population of phages as a function of frequency and intensity of environmental downturns affecting the ...
arxiv +1 more source
Phage therapy of pulmonary infections [PDF]
It is generally agreed that a bacteriophage-associated phenomenon was first unambiguously observed one-hundred years ago with the findings of Twort in 1915. This was independently followed by complementary observations by d'Hérelle in 1917. D'Hérelle's appreciation of the bacteriophage phenomenon appears to have directly led to the development of ...
openaire +3 more sources
Mimicking Biochemical Traits with a Synthetic Lipid Nanoparticles SARS‐COV‐2 Model
A synthetic virus model developed using lipid nanoparticles, which incorporate encapsulated mRNA and nucleocapsid (N) protein along with surface‐conjugated spike (S) protein, mimics the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), allowing for the advancement of diagnostic product assessment.
Ignasia Handipta Mahardika+7 more
wiley +1 more source
Treatment of infections caused by bacteria has become more complex due to the increasing number of bacterial strains that are resistant to conventional antimicrobial therapy.
Marek Straka+2 more
doaj +1 more source
Phages and human health: More than idle hitchhikers [PDF]
Bacteriophages, or phages, are viruses that infect bacteria and archaea. Phages have diverse morphologies and can be coded in DNA or RNA and as single or double strands with a large range of genome sizes. With the increasing use of metagenomic sequencing
Baldridge, Megan T+2 more
core +2 more sources
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang+4 more
wiley +1 more source