Results 121 to 130 of about 116,257 (347)
What are the limitations on the wider therapeutic use of phage? [PDF]
, 2013 Bacterial resistance to antibiotics poses a serious health threat. Since research into new antibiotics is not progressing at the same rate as the development of bacterial resistance, widespread calls for alternatives to antibiotics have been made.
Henein, Alexandra
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Perspectives of Phage–Eukaryotic Cell Interactions to Control Epstein–Barr Virus Infections
Frontiers in Microbiology, 2018 Recently, leading medical journals emphasized the importance of further studies on the potential application of bacterial viruses (phages) for the treatment of antibiotics-resistant infections outlining the present status of the therapy and perspectives ...
Andrzej Górski +10 more
doaj +1 more source
The Prevalence and Control of Bacillus and Related Spore-Forming Bacteria in the Dairy Industry [PDF]
, 2015 peer-reviewedMilk produced in udder cells is sterile but due to its high nutrient content, it can be a good growth substrate for contaminating bacteria. The quality of milk is monitored via somatic cell counts and total bacterial counts, with prescribed ...
Beresford, Tom +5 more
core +1 more source
Antibody‐Empowered Nanomedicine for Precise Biomedical Applications
Advanced Science, EarlyView.This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen +7 more
wiley +1 more source
Virology JournalBackground Pan-drug resistance (PDR) is a ticking time bomb, as it causes high human hospitalizations and mortality rates. For instance, Pseudomonas aeruginosa is associated with significant rates of urinary tract infections (UTIs) due to several reasons
Amira A. Mohamed +2 more
doaj +1 more source
Using millimeter‐waves for rapid detection of pathogenic bacteria in food based on bacteriophage
Engineering Reports, 2019 The accessibility of a rapid method for detection and identification of food‐borne pathogens is crucial for food industry worldwide. Antibiotic resistance bacteria (eg, E. coli) that can enter the food chain in different ways, can indeed survive on foods
Kamel S. Sultan +3 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2019 Atypical enteropathogenic E. coli (aEPEC) is a group of diarrhoeagenic Escherichia coli with high diversity of serogroups, which lack the bundle-forming pili (BFP) and genes encoding for shiga toxins.
Peter Kotsoana Montso +2 more
doaj +1 more source
Phage Therapy in the 21st Century: Is There Modern, Clinical Evidence of Phage-Mediated Efficacy? [PDF]
, 2021 Stephen T. Abedon +2 more
openalex +1 more source
Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity
Advanced Science, EarlyView.TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao +14 more
wiley +1 more source