Results 101 to 110 of about 2,642,573 (281)

Between Centralization and Fragmentation: The Past, Present, and Future of Phage Collections

International audienceDespite over a century of collecting bacteriophages, there has been a persistent lack of interest in systematically cataloging resulting phage banks.
Resch, Grégory, Kirchhelle, Claas, Laurent, Frédéric, Moineau, Sylvain, Hodges, Francesca, Rohde, Christine, Debarbieux, Laurent, Brives, Charlotte, Martins, Ana Filipa Moreira, Kirchhelle, C., Hodges, F.E., Resch, G., Brives, C., Laurent, F., Martins, AFM, Moineau, S., Rohde, C., Debarbieux, L., Hodges, Francesca E., et al.   +19 more
core   +1 more source

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

Advanced Science, EarlyView.
(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen, Zhenguo Cao, Zenan Wang, Liang Chen, Jiahao Zhang, Linjie Zeng, Boren Tan, Hengyuan Li, Jiashan Lai, Jiangchu Lei, Fanglu Chen, Peng Lin, Zhenxuan Shao, Zhan Wang   +13 more
wiley   +1 more source

An Alternative Approach Against Resistent Infections: Long-Term Bacteriophage Therapy in Cystic Fibrosis

Viruses
Cystic fibrosis (CF) is an autosomal recessive genetic disorder that disrupts ion transport across epithelial surfaces, impairing mucociliary clearance and predisposing patients to chronic, often refractory bacterial infections.
Lia Nadareishvili, Nata Nakaidze, Mariam Dadiani, Dea Nizharadze, Elisabed Zaldastanishvili, Nana Balarjishvili, Lika Leshkasheli, Mzia Kutateladze   +7 more
doaj   +1 more source

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

Advanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu, Xuting Zheng, Huinan Tong, Ying Liu, Xiaoxi Fan, Miao Xu, Ziyan Zhang, Li Zhang, Mingyan Liu, Ting Du, Heran Li, Guojun Liu   +11 more
wiley   +1 more source

Phage therapy for Escherichia coli urinary tract infections: selecting therapeutic phages and understanding resistance mechanisms in urine [PDF]

Urinary tract infections (UTIs) affect a large proportion of the human and canine population. Due to rising levels of antibiotic resistance, empirical treatment with conventional antibiotics may fail, which can increase the probabilities of recurrence ...
Park de la Torriente, Alba
core   +1 more source

Combatting Antibacterial Resistance With Phage Therapy [PDF]

, 2020
Phage therapy is the use of viruses to treat bacterial infections. This therapeutic method offers a viable solution to antibiotic resistance among pathogenic bacteria. In this review, we discuss the strengths and weaknesses of phage therapy.
Line, Linda
core   +1 more source

Correction: Morphological, biological, and genomic characterization of Klebsiella pneumoniae phage vB_Kpn_ZC2

Virology Journal, 2023
Mohamed S. Fayez, Toka A. Hakim, Bishoy Maher Zaki, Salsabil Makky, Mohamed Abdelmoteleb, Kareem Essam, Anan Safwat, Abdallah S. Abdelsattar, Ayman El-Shibiny   +8 more
doaj   +1 more source

Novel strategies for vancomycin-resistant Enterococcus faecalis biofilm control: bacteriophage (vB_EfaS_ZC1), propolis, and their combined effects in an ex vivo endodontic model

Annals of Clinical Microbiology and Antimicrobials
Background Endodontic treatment failures are predominantly attributed to Enterococcus faecalis (E. faecalis) infection, a Gram-positive coccus. E. faecalis forms biofilms, resist multiple antibiotics, and can withstand endodontic disinfection protocols ...
Toka A. Hakim, Bishoy Maher Zaki, Dalia A. Mohamed, Bob Blasdel, Mohamed A. Gad, Mohamed S. Fayez, Ayman El-Shibiny   +6 more
doaj   +1 more source

The human phageome: niche-specific distribution of bacteriophages and their clinical implications

Applied and Environmental Microbiology
Bacteriophages (phages) play a crucial role in shaping the composition and diversity of the human microbiome across various body niches. Recent advancements in high-throughput sequencing technologies have enabled comprehensive analysis of the human ...
Izabela Rybicka, Zuzanna Kaźmierczak
doaj   +1 more source

Molecular Evaluation of High Fluoroquinolone Resistant Genes in Endemic Cases of Shigellosis, Northeast Part of Karnataka, India

Annals of Global Health, 2017
ObjectivesShigellosis is an acute infection of the intestine caused by bacteria in the genus 'Shigella' and also an important cause of diarrhea in developing countries.
Prabhurajeshwar C, Pramod Desai, Kelmani Chandrakanth R   +2 more
doaj   +1 more source