Results 121 to 130 of about 2,642,573 (281)
Virology JournalBackground Pan-drug resistance (PDR) is a ticking time bomb, as it causes high human hospitalizations and mortality rates. For instance, Pseudomonas aeruginosa is associated with significant rates of urinary tract infections (UTIs) due to several reasons
Amira A. Mohamed +2 more
doaj +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Virus‐like particles (VLPs) are a promising modality with extensive applications in prophylactic and therapeutic vaccine design. Human Papillomavirus (HPV) vaccines are one such example where VLP vaccine applications have led to the successful reduction in HPV‐associated diseases, such as cervical cancer.
Nicholas Samuelson +5 more
wiley +1 more source
Phage resistance profiles of AB-phages treated Acinetobacter baumannii: implications for phage therapy strategies [PDF]
Introduction: Phage therapy is a promising alternative for combating multidrug-resistant bacteria, including Acinetobacter baumannii (AB). However, the development of phage-resistant variants after treatment, particularly when using phage cocktails ...
Umaporn Yordpratum +3 more
core +1 more source
Induction and Enhancement of Bacteriocin Production (Review)
Biotechnology and Bioengineering, EarlyView.ABSTRACT Conventionally, bacteriocins are produced by microorganisms on complex substrates, released as semi‐purified preparations or crude fermentates. These bacteriocin‐containing products often exhibit unsatisfactory purity, low active‐substance content, and high production costs, limiting their commercialization and use. This review aims to analyze
Oksana Knysh, Artur Martynov
wiley +1 more source
Elucidating Key Steps of Pseudomonas Aeruginosa Infection by DEV Lytic Phage for Phage Therapy
Phage therapy is a promising treatment for infections caused by antibiotic resistant bacteria including Pseudomonas aeruginosa (Pa). Studying the biology of phages for therapy is important to make it safe and effective.
AMINIAN S. +5 more
core
Editorial overview: Special issue on phage therapy
Phage therapy, the use of bacteriophages to control infectious diseases caused by bacteria, has gained a renewed interest due to the emergence and spread of antibiotic resistance. While this clinical practice is well established in many Eastern countries,
Pirnay, Jean Paul +3 more
core +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
BMEMat, EarlyView.This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
VirusesPhage therapy shows promise as an adjunct to antibiotics for treating Staphylococcus aureus infections. We previously reported a combined flucloxacillin/two-phage cocktail treatment selected for resistance to podovirus phage 66 in a rodent model of ...
Jérémy Cherbuin +3 more
doaj +1 more source
Overview and Outlook of Phage Therapy and Phage Biocontrol [PDF]
Phage Therapy, used in synergy with antibiotics, has the potential to combat the global threat of antimicrobial resistance. However, a proper regulatory frame for the approval and marketing authorisation of phage preparations is missing. The current long
PIRNAY Jean-Paul +2 more
core +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source