Results 141 to 150 of about 114,190 (344)

The Importance of Being Imperfect: Structure and Function of Bacterial Amyloid

open access: yesAdvanced Science, EarlyView.
Functional bacterial amyloids such as CsgA and FapC have been widely studied to understand the relationship between aggregation and function. The recently solved structure of FapC reveals a Greek‐key motif in which extensive hydrogen bonding and packing interactions formed by residues in conserved imperfect repeats stabilize a β‐solenoid core.
Samuel Peña‐Díaz   +12 more
wiley   +1 more source

Isolation and characterization of phages ΦZC2 and ΦZC3 against carbapenem-resistant Acinetobacter baumannii, and efficacy of ΦZC3 on A549 cells

open access: yesVirology Journal
Background Acinetobacter baumannii is an opportunistic pathogen and a major causative agent of hospital-acquired infections. This pathogen can acquire various antibiotic resistance genes, including those conferring resistance to last-resort antibiotics ...
Kareem Essam   +7 more
doaj   +1 more source

SMart Nanoparticle–Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing

open access: yesAdvanced Science, EarlyView.
The integrated system, comprising bacterial‐targeted photothermal nanoparticles (Fe2O3‐CS@RBP) and multifunctional hydrogels (PAOC‐3@BA) modules, achieves rapid wound healing within one week. This work introduces a smart therapeutic platform that integrates bacterial targeting, self‐regulating photothermal therapy, tissue adhesion, and stimulus ...
Hongping Wan, Huirong Tan, Xinghong Zhao
wiley   +1 more source

Rational Design of a Potent Two-Phage Cocktail Against a Contemporary Acinetobacter baumannii Strain Recovered from a Burned Patient at the Lausanne University Hospital

open access: yesViruses
Acinetobacter baumannii is a critical public health threat, particularly with the rise in multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains that limit treatment options.
Hugues de Villiers de la Noue   +3 more
doaj   +1 more source

Emerging applications of phage therapy and fecal virome transplantation for treatment of Clostridioides difficile infection: challenges and perspectives [PDF]

open access: gold, 2023
Hamideh Raeisi   +6 more
openalex   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

open access: yesAdvanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen   +10 more
wiley   +1 more source

Harnessing Large Language Models to Advance Microbiome Research: From Sequence Analysis to Clinical Applications

open access: yesAdvanced Intelligent Discovery, EarlyView.
Large language models are transforming microbiome research by enabling advanced sequence profiling, functional prediction, and association mining across complex datasets. They automate microbial classification and disease‐state recognition, improving cross‐study integration and clinical diagnostics.
Jieqi Xing   +4 more
wiley   +1 more source

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