Results 161 to 170 of about 116,257 (347)

Generation of a nanobody against HER2 tyrosine kinase using phage display library screening for HER2-positive breast cancer therapy development [PDF]

open access: bronze, 2021
Thomanai Lamtha   +7 more
openalex   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan   +3 more
wiley   +1 more source

Tumor Cell Migration May Be an Inherent “Foraging” Behavior

open access: yesMedicine Advances, EarlyView.
Tumor cells gradually form pseudopodia, migrate to necrotic cells, make contact with them, and absorb necrotic cell debris. During this migration, small vesicles formed by dying tumor cells also gradually migrate toward living tumor cells. Once the nutrients from the necrotic cells have been completely absorbed, the living tumor cells will leave ...
Fuqian Zhao   +4 more
wiley   +1 more source

Rapid Isolation of Bacteriophages: Steps Towards Phage Therapy

open access: diamond, 2019
Idah Sithole‐Niang   +2 more
openalex   +1 more source

Principles and Practice Guidelines of Microbiota Medicine: Statements From the CHINAGUT Conference

open access: yesMicrobiota Medicine Research, EarlyView.
The 2025 CHINAGUT Conference convened a panel of 48 clinicians from 39 hospitals in 5 countries to develop 15 key statements, aimed at providing clinicians, educators, and healthcare administrators with a comprehensive framework to advance education, clinical practice, research, and public popularization in microbiota medicine.
Faming Zhang   +52 more
wiley   +1 more source

Washed Microbiota Transplantation Using Ileocolic Transendoscopic Enteral Tubing Versus Basic Treatments for Intestinal Inflammatory Obstruction in Crohn's Disease: A Multicenter Concurrent Controlled Trial

open access: yesMicrobiota Medicine Research, EarlyView.
Washed microbiota transplantation using ileocolic transendoscopic enteral tubing was identified as a viable, effective and safe bridge treatment for intestinal inflammatory obstruction in Crohn's disease, demonstrating significantly higher 28‐day improvement rates compared to basic treatment.
You Yu   +11 more
wiley   +1 more source

Refining responsive antimicrobial nanomaterials from random peptide libraries via machine learning

open access: yesResponsive Materials, EarlyView.
Machine learning refines random peptide mixtures into responsive antimicrobial cocktails, yielding enhanced antibacterial efficacy and improved in vivo therapeutic effects. Abstract Antimicrobial resistance has evolved into one of the most serious threats to global public health, yet generalizable routes for refining random peptide mixtures (RPMs) into
Lin Wang   +7 more
wiley   +1 more source

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