Results 181 to 190 of about 2,642,573 (281)

A guide to the ecological limitations of phage therapy of bacterial biofilms: Is what's best for the phage best for the physician?

The FEBS Journal, EarlyView.
Bacteriophages—viruses that kill bacteria—are promising weapons against bacterial biofilms: sessile communities notoriously resistant to antibiotics. Yet phages evolved not so much to eradicate bacteria as to obtain new bacteria to infect. That goal, however, may conflict with the physician's objective of complete bacterial clearance.
Stephen T. Abedon
wiley   +1 more source

Precision phage therapy in the AI/ML era: a systematic review of discovery-to-clinical translation evidence. [PDF]

Front Microbiol
Alharbi NM.
europepmc   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Phage Therapy for a Refractory and Multidrug-resistant Equine Surgical Site Infection. [PDF]

Int J Vet Sci Med
Alverson D, Gustafson G, Duesterdiec-Zelmer KF, Kamm JL, Danelishvili L.   +4 more
europepmc   +1 more source

Phage therapy

Journal of Pharmacy and Pharmacology, 1998
openaire   +1 more source

Modulation of sebocyte function in acne: A pathway‐inclusive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis, Apostolos Pappas, Katja Martin, Mauro Picardo   +3 more
wiley   +1 more source

Phage Therapy in Gastrointestinal Diseases: Current Status and Challenges. [PDF]

Int J Mol Sci
Zhang S, Zhang Y.
europepmc   +1 more source

Efficacy of Ccombody as an Immunoprophylaxis Strategy: Impact on Immune Gene Expression of Pacific White Shrimp (Penaeus vannamei) Against Acute Hepatopancreatic Necrosis Disease (AHPND)

Journal of Fish Diseases, EarlyView.
ABSTRACT Acute hepatopancreatic necrosis disease (AHPND) is caused by a plasmid bearing strain of Vibrio parahaemolyticus (VpAHPND), which produces PirA and PirB toxins that specifically target and damage hepatopancreatic and epithelial cells of the shrimp gastrointestinal tract.
Prawporn Thaijongrak, Kasemsuk Kitisriworapun, Theerapat Damrongsakul, Napat Huttayanan, Thitipan Juntong, Andrew P. Shinn, Tae Sung Jung, Surasak Jittakhot, Wanna Sirimanapong   +8 more
wiley   +1 more source

Phage Therapy: Application and Related Problems-A Review. [PDF]

Life (Basel)
Sippel K, Velimirov B.
europepmc   +1 more source

20th Anniversary of human‐induced pluripotent stem cells and the role of microscopy

Journal of Microscopy, EarlyView.
Abstract It has been 20 years since the pioneering work of Shinya Yamanaka and Kazutoshi Takahashi at Kyoto University led to the first successful generation of induced pluripotent stem cells (iPSCs) from mouse embryonic and adult fibroblast cells. iPSCs have the capacity to differentiate into any type of cell in the human body, and as such, they have ...
Philomena Hallford, Colette J. Mustard, Nicole Brace, Antonia L. Pritchard   +3 more
wiley   +1 more source