Results 201 to 210 of about 2,642,573 (281)

Antibodies targeting phage fiber and nozzle proteins impair Acinetobacter baumannii phage therapy by blocking infection and promoting immune clearance. [PDF]

PLoS Biol
Xue H, Li X, Rao G, Hu F, Zhong M, Miernikiewicz P, Qiu R, Cao S, Dąbrowska K, Yang H.   +9 more
europepmc   +1 more source

Periodontal Salutogenesis: Why Are Some People Resistant to Oral Microbial Dysbiosis and Destructive Inflammation?

Journal of Periodontal Research, EarlyView.
Emerging evidence suggests that periodontal health is not simply the absence of disease, but the result of a dynamic interaction between biological resilience, healthy lifestyles, adaptive coping mechanisms, and supportive environments. This results in a strong sense of coherence, which is not only a psychological state but also a biological state ...
Bruno G. Loos, Magda Feres, William V. Giannobile, Hatice Hasturk, Egija Zaura   +4 more
wiley   +1 more source

Effect of human urinary microenvironment and fluid flow on antibiotic and phage therapy efficacy against uropathogenic Escherichia coli. [PDF]

Nat Commun
Garcia Maset R, Crowther A, Chu V, De Grandi D, Jariah ROA, Yoon J, Blumgart D, Hodek MAE, Torelli F, Yuen N, Murray BO, Holden KL, Bancroft J, Pasquina-Lemonche L, Alghamd SNH, Millard AD, LuTheryn G, Haines MEK, Clokie MRJ, Pollara G, Stride E, Carugo D, Rohn JL.   +22 more
europepmc   +1 more source

Preclinical Target Animal Safety Evaluation of Veterinary Monoclonal Antibodies: Principles, Methods, and Interpretation

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Monoclonal antibodies (mAbs) represent a rapidly expanding pharmaceutical class in veterinary medicine, with several products now authorized for use in dogs and cats. Limited published articles and veterinarian exposure to the principles of drug development present challenges in interpreting published safety evaluations that inform product ...
Adam Werts, Matthew Kuhn, Lauren Bessey, Alicia Braxton Hickman, Emily Chory, John Mitchell, Kirby Pasloske   +6 more
wiley   +1 more source

Combined phage therapy and faecal microbiota transplantation to treat recurrent urinary tract infection: a case series. [PDF]

Nat Microbiol
McCallin S, Classen AY, Lieberknecht-Jouy SC, Abdula F, Dugas S, Gross O, Koliwer-Brandl H, Lassen S, Scheidegger J, Dunne M, Kahles A, Eigler J, Farowski F, Higgins PG, Milek S, Chemych O, Du J, Loessner MJ, Kessler TM, Vehreschild MJGT, Leitner L, Biehl LM.   +21 more
europepmc   +1 more source

Bacteriophage P22 Virus‐Like Particles as Nanoscale Protein Scaffolds for Plant Synthetic Biology

Plant Biotechnology Journal, EarlyView.
ABSTRACT Advancing the utility of plant synthetic biology requires the continued development of protein engineering tools. Self‐assembling protein compartments, such as virus‐like particles (VLPs), provide versatile scaffolds for synthetic biology. However, few plant‐expressed VLPs have demonstrated broad amenability to protein engineering, restricting
Maxim D. Harding, Mark A. Jackson, Edward K. Gilding, David J. Craik, Frank Sainsbury, Nicole Lawrence   +5 more
wiley   +1 more source

From hype to hope: reanimating phage therapy through evidence-based multidisciplinarity. [PDF]

Nat Commun
Petrović-Fabijan A, Abedon ST.
europepmc   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Management of Diabetic Foot Infections Using Phage Therapy. [PDF]

Infect Drug Resist
Nazari M, Shokoohizadeh L.
europepmc   +1 more source