Results 211 to 220 of about 2,642,573 (281)

Putting the brakes on muscle growth: Myostatin as regulator of disuse atrophy

Experimental Physiology, EarlyView.
Abstract Skeletal muscle is a highly plastic tissue that rapidly adapts to changes in mechanical loading and metabolic activity. Periods of inactivity, including bed rest, limb immobilization or microgravity, induce a pronounced loss of muscle mass and function.
Derk H. C. Nieuwenhuijsen, Moritz Eggelbusch, Rob C. I. Wüst   +2 more
wiley   +1 more source

Phage Therapy in Combating Multidrug-Resistant Gram-Negative Pathogens: A Scoping Review. [PDF]

Pharmaceuticals (Basel)
Sukri A, Lopes BS, Hanafiah A.
europepmc   +1 more source

Concordance of Microbiological and Histopathological Examination of Bone Biopsies in Diagnosing Diabetic Foot Osteomyelitis, a Systematic Review

Journal of Foot and Ankle Research, Volume 19, Issue 4, December 2026.
ABSTRACT Background Diabetic foot osteomyelitis (DFO) is a serious complication of diabetic foot ulcers and is associated with increased risk of amputation, morbidity, and mortality. Bone biopsy remains the most definitive diagnostic modality, yet controversy persists over its diagnostic utility This study reviews the diagnostic concordance of ...
Levi Kadiri, Anthony Maher, Andy Bridgen
wiley   +1 more source

Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis. [PDF]

J Gastroenterol Hepatol
Chen J, Duan C, Zhang K, Liu J, Han C.
europepmc   +1 more source

Charting the Voyages of Acinetobacter baumannii in Southeast Asia: Mapping the Regional Genomic Landscape

MicrobiologyOpen, Volume 15, Issue 6, December 2026.
A genomic analysis of 853 Southeast Asian Acinetobacter baumannii isolates reveals the regional dominance of the highly resistant Global Clone 2 (GC2) lineage. Characterised by diverse mobile elements and distinct phage defenses, these findings establish a critical baseline to guide future surveillance and broader regional sampling.
Soo Sum Lean, Prasit Palittapongarnpim, Stuart C. Clarke, Chew Chieng Yeo   +3 more
wiley   +1 more source

Spot-on phage therapy: stable formulations, smarter dosing for topical phage application. [PDF]

Front Cell Infect Microbiol
Sandhu JS, Parida A.
europepmc   +1 more source

Engineering Mosaic T7 Bacteriophages for Dual Peptide Display to Enable Cellular Targeting and Ligand‐Directed Protein Capture

Biotechnology Journal, Volume 21, Issue 11, November 2026.
Graphical Abstract and Lay Summary A mosaic T7 phage platform enables simultaneous display of two independent peptides on the same phage particle. The modular design integrates receptor targeting, protein capture, and tissue‐directed in vivo phage display, establishing a versatile methodology for multifunctional phage engineering, receptor ...
Luca Marchetti, Kristina Põšnograjeva, Prakash Lingasamy, Karlis Pleiko, Ivar Ilves, Tambet Teesalu   +5 more
wiley   +1 more source

Bispecific NK‐Cell Engager Targeting TP53 Mutation Through Integration of a TCR‐mimic Antibody

MedComm, Volume 7, Issue 11, November 2026.
Most existing NK cell engagers (NKCEs) target tumor‐associated antigens (TAAs), risking on‐target, off‐tumor toxicity. We engineered a novel NKCE termed C33×CD16, a single‐chain diabody (scDb) constructed by fusing TCR‐mimic antibody C33‐Ab (targeting p53R175H/HLA‐A*02:01) to the scFv of 3G8 (anti‐CD16 antibody) (a).
Hanfei Wu, Zhe Zhao, Li Zhang, Xuan Xiong, Mengdie Yang, Weiping Ge, Danyue Zhi, Xiaobin Cao, Chuanqian Yi, Yong Qiao, Junjun Cao, Yan Mei, Shiping Jiao, Quan Liu, Hao Zhou, Zhongjuan Xu, Guangli Suo   +16 more
wiley   +1 more source

Phage Therapy as an Alternative Strategy Against Pseudomonas aeruginosa: A Narrative Review of Preclinical and Clinical Evidence. [PDF]

Microbiologyopen
Cunha GAD, Amaral RP, Dos Santos ALC, Aio BRF, Durante MFR, Malaquias LCC, de Freitas Almeida GM, Coelho LFL.   +7 more
europepmc   +1 more source

Artificial Intelligence–Driven Graph Methods for Microbiome Research: A Systematic Review

WIREs Mechanisms of Disease, Volume 18, Issue 6, November/December 2026.
Multi‐omics and microbiome‐derived datasets were converted into deterministic and probabilistic network representations for downstream classical graph analysis and graph representation learning. This framework enables link prediction, relationship discovery, and node clustering to improve interpretation of complex biological interactions.
Cedrique Shum‐Tim, Paromita Islam, Jacqueline L. Boyajian, Ahmed Abosalha, Amal Kassab, Madison Santos, Kinaan Aamir Khan, Kiri Stern, Amin Emad, Satya Prakash   +9 more
wiley   +1 more source