Results 191 to 200 of about 72,592 (256)
The building blocks of phage therapy: from lytic phage identification to preclinical validation against antimicrobial-resistant critical priority bacteria. [PDF]
Vale FF.
europepmc +1 more source
ABSTRACT Background Musculoskeletal complications in type 2 diabetes (T2DM) are inadequately captured by body mass index (BMI). Waist‐to‐BMI ratio (WBR) may better reflect adverse body composition. We examined cross‐sectional and longitudinal associations between WBR and musculoskeletal disorders in T2DM.
Yongze Zhang +8 more
wiley +1 more source
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos +11 more
wiley +1 more source
The future of phage therapy in the USA. [PDF]
Berryhill BA +3 more
europepmc +1 more source
EV‐LYSG101: Extracellular Vesicles Loaded With Lysin LYSG101 for Potent Anti‐Staphylococcal Activity
ABSTRACT Biofilm‐associated staphylococcal infections remain exceptionally difficult to treat due to the presence of resilient staphylococcal biofilms and the limited effectiveness of currently available antibiotics. To combat persistent infections, providers are often forced to use prolonged courses of combination antimicrobial therapies that have ...
Dominique B. Hoelzinger +6 more
wiley +1 more source
Phage therapy for intestinal infections: efficacy, challenges, and future directions in translational research. [PDF]
Wang X +12 more
europepmc +1 more source
The Dual Role of the Gut Microbiota in Cancer Chemoresistance
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi +3 more
wiley +1 more source
Phage Therapy in Plant Disease Management: 110 Years of History, Current Challenges, and Future Trends. [PDF]
Pertics BZ +7 more
europepmc +1 more source
Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives
The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng +9 more
wiley +1 more source

