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Clinical Infectious Diseases, 2023
BACKGROUND Antibiotic resistance (AMR) is undermining modern medicine, a problem compounded by bacterial adaptation to antibiotic pressures. Phages are viruses that infect bacteria.
S. Green+17 more
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BACKGROUND Antibiotic resistance (AMR) is undermining modern medicine, a problem compounded by bacterial adaptation to antibiotic pressures. Phages are viruses that infect bacteria.
S. Green+17 more
semanticscholar +1 more source
Drug Discovery Today, 2009
There is a renaissance of interest in the antimicrobial potential of phages as more pathogens become multiply antibiotic resistant. Phage therapy is not a new concept, and it is important to ask why it is not part of the current repertoire of western medicine despite the fact that it has been continuously and extensively used in Eastern Europe for ...
John N, Housby, Nicholas H, Mann
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There is a renaissance of interest in the antimicrobial potential of phages as more pathogens become multiply antibiotic resistant. Phage therapy is not a new concept, and it is important to ask why it is not part of the current repertoire of western medicine despite the fact that it has been continuously and extensively used in Eastern Europe for ...
John N, Housby, Nicholas H, Mann
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2023
Cancer is currently a global health challenge, characterized by dysfunction of organs due to the uncontrolled growth of cells exponentially. The therapies used to treat cancer in patients so far are widely used. However, there are also some problems, such as the high cost of surgery and chemotherapy.
Hue Vu, Thi+3 more
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Cancer is currently a global health challenge, characterized by dysfunction of organs due to the uncontrolled growth of cells exponentially. The therapies used to treat cancer in patients so far are widely used. However, there are also some problems, such as the high cost of surgery and chemotherapy.
Hue Vu, Thi+3 more
openaire +2 more sources
Current Pharmaceutical Biotechnology, 2010
Phage therapy--application of bacteria-specific viruses to reduce densities of pathogenic or nuisance bacteria--is a two-step process involving phage penetration to target bacteria followed by bacteria killing. Any analysis of these steps is inherently ecological as they represent phage-environment interactions, i.e., between phages and bacteria as ...
Cameron Thomas-Abedon, Stephen T. Abedon
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Phage therapy--application of bacteria-specific viruses to reduce densities of pathogenic or nuisance bacteria--is a two-step process involving phage penetration to target bacteria followed by bacteria killing. Any analysis of these steps is inherently ecological as they represent phage-environment interactions, i.e., between phages and bacteria as ...
Cameron Thomas-Abedon, Stephen T. Abedon
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Reviews in Medical Virology, 2019
SummaryBacteriophages or phages, being the most abundant entities on earth, represent a potential solution to a diverse range of problems. Phages are successful antibacterial agents whose use in therapeutics was hindered by the discovery of antibiotics.
Sana Rehman+4 more
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SummaryBacteriophages or phages, being the most abundant entities on earth, represent a potential solution to a diverse range of problems. Phages are successful antibacterial agents whose use in therapeutics was hindered by the discovery of antibiotics.
Sana Rehman+4 more
openaire +3 more sources
2012
Phage therapy is the clinical or veterinary application of bacterial viruses (bacteriophages) as antibacterial "drugs." More generally, phages can be used as biocontrol agents against plant as well as foodborne pathogens. In this chapter, we consider the therapeutic use of phage cocktails, which is the combining of two or more phage types to produce ...
Benjamin K Chan, Stephen T. Abedon
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Phage therapy is the clinical or veterinary application of bacterial viruses (bacteriophages) as antibacterial "drugs." More generally, phages can be used as biocontrol agents against plant as well as foodborne pathogens. In this chapter, we consider the therapeutic use of phage cocktails, which is the combining of two or more phage types to produce ...
Benjamin K Chan, Stephen T. Abedon
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Phage therapy is an experimental method of treatment of antibiotic-resistant bacterial infections. Patients can get access to phages either by enrolling in a clinical trial or during compassionate treatment. Very few clinical trials of phages have been conducted to date.
Andrzej Górski+2 more
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Phage Choice, Isolation, and Preparation for Phage Therapy
Current Pharmaceutical Biotechnology, 2010Phage therapy is the use of bacteriophages--viruses that use bacteria as their host cells--as biocontrol agents of bacteria. Currently, phage therapy is garnering renewed interest as bacterial resistance to antibiotics becomes widespread. Historically, phage therapy was largely abandoned in the West in the 1940s due to the advent of chemical ...
Jason J. Gill, Paul Hyman
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