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Models of phage growth and their applicability to phage therapy
Journal of Theoretical Biology, 2004Phage therapy is complicated by the self-replicating nature of phage. It is difficult to extrapolate from in vitro phage growth data to in vivo expectations, difficult to interpret in vivo data and difficult to generalize from one in vivo situation to another.
Christine A. Butts +2 more
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Synthetic phage and its application in phage therapy
2023Synthetic phage analysis has been implemented in progressive various areas of biology, such as genetics, molecular biology, and synthetic biology. Many phage-derived technologies have been altered for developing gene circuits to program biological systems.
Ajay, Kumar, Anuj, Yadav
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2011
Phage therapy, which can be described as a phage-mediated biocontrol of bacteria (or, simply, biocontrol), is the application of bacterial viruses-also bacteriophages or phages-to reduce densities of nuisance or pathogenic bacteria. Predictive calculations for phage therapy dosing should be useful toward rational development of therapeutic as well as ...
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Phage therapy, which can be described as a phage-mediated biocontrol of bacteria (or, simply, biocontrol), is the application of bacterial viruses-also bacteriophages or phages-to reduce densities of nuisance or pathogenic bacteria. Predictive calculations for phage therapy dosing should be useful toward rational development of therapeutic as well as ...
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History of Phage Research and Phage Therapy [PDF]
, 2014 Bacteriophages are widely distributed and exhibit dramatic manifestations both in liquid cultures and on solid media. Felix d’Herelle’s research had two important directions, focusing on (i) the therapeutic use of the phage in infectious diseases and (ii) the biological nature of the bacteriophage itself. From his first studies of clinical samples from
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Phage Therapy: Future Inquiries
Postdoc Journal, 2013Western scientists have steadily been gaining interest in phage therapy since the mid-1980's due to the rising problem of antibiotic resistance. Its introduction in the 20th century by Felix d'Herelle marked the beginning for the uses of bacteriophages as antibacterial agents.
Elisabeth Zachary +3 more
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Clinical Aspects of Phage Therapy
2012Phage therapy (PT) is a unique method of treatment of bacterial infections using bacteriophages (phages)-viruses that specifically kill bacteria, including their antibiotic-resistant strains. Over the last decade a marked increase in interest in the therapeutic use of phages has been observed, which has resulted from a substantial rise in the ...
Ryszard Międzybrodzki +12 more
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Safety and efficacy of phage therapy in difficult-to-treat infections: a systematic review.
Lancet. Infectious Diseases (Print), 2022S. Uyttebroek +16 more
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2014
Who really discovered bacteriophage? Ernest Hankin, a British scientist working in India in the nineteenth century, claimed that the lack of bacterial contamination in the Ganges River was due to the presence of anti-bacterial substance. The idea of using phage to counteract bacterial infections was promoted by Felix d’Herelle.
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Who really discovered bacteriophage? Ernest Hankin, a British scientist working in India in the nineteenth century, claimed that the lack of bacterial contamination in the Ganges River was due to the presence of anti-bacterial substance. The idea of using phage to counteract bacterial infections was promoted by Felix d’Herelle.
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The Renaissance of Phage Therapy
2011One morning in 1993, Carl Merril read an alarming article in The Washington Post. It told of the growing problem of antibiotic resistance, a story that had been creeping into the press since the early 1980s. From Tokyo to New York City, the Post wrote, hospitals were contending with a new breed of superbugs, bacteria that had grown immune to the ...
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