Results 111 to 120 of about 40,342 (348)
Advanced Science, EarlyView.CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu +13 more
wiley +1 more source
Superbugs and Superdrugs: A history of MRSA [PDF]
, 2008 Annotated and edited transcript of a Witness Seminar held on 11 July 2006. Introduction by Professor David Greenwood, University of Nottingham.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2008.©The Trustee of the ...
Reynolds, LA, Tansey, EM
core
PREPARATION AND ANTIGENICITY OF M PROTEIN RELEASED FROM GROUP A, TYPE 1 STREPTOCOCCAL CELL WALLS BY PHAGE-ASSOCIATED LYSIN [PDF]
, 1960 Fred S. Kantor, Roger M. Cole
openalex +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Characterization of Waterborne Outbreak–associated Campylobacter jejuni, Walkerton, Ontario
Emerging Infectious Diseases, 2003 The Walkerton, Canada, waterborne outbreak of 2000 resulted from entry of Escherichia coli O157:H7 and Campylobacter spp. from neighboring farms into the town water supply.
Clifford G. Clark +9 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT This special issue marking the University of Bath's 60th anniversary offers an opportunity to reflect on nearly a decade of research into the evolution of gene regulatory networks (GRNs) from members of the lab and elsewhere. Our goal is to understand how GRNs rewire and how new transcription factor (TF) functions evolve. Using an experimental
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source
Hayati Journal of Biosciences, 2015 Bacillus pumilus is a spore-forming bacteria that is rod-shaped, gram positive, and aerobic. B. pumilus produced pumilacidins, known to have toxic effects on epithelial cells.
ANIK KUSMIATUN +2 more
doaj +1 more source
Isolation of Phages and Phage Typing of Bacillus cereus.
Japanese Journal of Food Microbiology, 1998 Bacillus cereusのファージ型別セットを作製した.36株のパイロット株12, 14 を指示菌として, 土壌85検体から96のファージを分離した.保存安定性とパイロット株に対する溶菌パターンから選んだ11のファージは抗血清中和反応により5群に分けられた.そこで, 各群から5ファージ (φa, φb, φc, φd, φeと命名) を選び, 型別セットとした.このセットを用いて, ファージ濃度1×RTD (routine test dilution) および100×RTDでは, 36種のH抗原パイロット株は17の型 (83.3%型別) および11の型 (100%型別) に, 魚粕由来25株は9の型 (48.0%型別) および9の型 (100%型別) に, 土壌由来株100株は24の型 (79.
Mikio SHIMIZU +3 more
openaire +2 more sources
Physiological Aspects of Genetics [PDF]
, 1954 A considerable amount of evidence indicates that desoxyribonucleic acid is capable of duplicating itself, a property also possessed by genes. (By a self-duplicating material, we mean one which plays some essential role in its own production.) Watson ...
Horowitz, N. H., Owen, Ray D.
core +1 more source
Advanced Science, EarlyView.A self‐regulated Escherichia coli Nissle 1917 strain equipped with a dual‐key genetic circuit achieved antibiotic‐free stability and programmable lysis for therapeutic protein delivery. By co‐expressing an IL‐2 mutant and Amuc_1100, the engineered bacteria restored immune balance and epithelial integrity, providing a safe and precise approach for ...
Shuaijie Ding +6 more
wiley +1 more source