Results 121 to 130 of about 22,867 (253)

Mind the gap! Typing <i>Escherichia coli</i> O157:H7 in the pre- and post-genomic revolution eras. [PDF]

Microb Genom
Poh CJ, Greig DR, Chattaway MA, Ready D, Jenkins C.   +4 more
europepmc   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Microbiome‐mediated plant‐soil feedbacks as a tool for resilient agriculture

iMetaOmics, EarlyView.
Translating plant‐soil feedbacks (PSFs) into reliable agricultural management requires shifting from input‐dependent practices toward endogenous, process‐driven crop resilience. To bridge this gap, we propose a predictive framework centered on three strategic interventions: engineering the crop holobiont, diversifying the soil habitat, and deploying ...
Muhammad Asif, Hazrat Bilal, Min Xiao, Lei Dong, Wen‐Jun Li   +4 more
wiley   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

iMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang, Jianhong Tian, Wenyan Zhao, Siqin Zhang, Lixuan Xiang, Meiqing Yang, Lu Liu, Yazhou Huang, Ningyun Zhang, Lei Sun, Peng Xie, Nanyu Kuang, Hong Zhou, Chengfeng Qiu, Jun Yan, Xiaocheng Jiang, Qiang Tu, Yun Wang, Haoliang Hu, Youming Zhang   +19 more
wiley   +1 more source

Bioinformatics-Driven Systematic Molecular Typing and Rapid qPCR Detection of <i>Escherichia coli</i> Phages: Preliminary Validation with Isolates from Cattle Farms in Xinjiang. [PDF]

Pathogens
Dang X, Cao X, Li L, Yang L, Zhao L, Sheng J, Zheng X, Zhai C, Song J, Wu W, Wang Y, Zhang S.   +11 more
europepmc   +1 more source

Viruses in the sediments around the trenches harbor diverse survival mechanisms

iMetaOmics, EarlyView.
Deep‐sea trenches are the deepest and most isolated environments in the global ocean but the diversity and adaptation of the viral communities remain poorly characterized. In this study, 5563 viral operational taxonomic units (vOTUs) were identified from sediments of the Yap Trench and Western Caroline Basin.
Yue Su, Hao Yu, Shujuan Sun, Kaiyang Zheng, Ziyue Wang, Chen Gao, Guangxue Li, Xiaoshou Liu, Hongbing Shao, David Paez‐Espino, Andrew McMinn, Yantao Liang, Min Wang   +12 more
wiley   +1 more source

Genomic Map of Escherichia coli and Single Nucleotide Polymorphism Markers in Colorectal Cancer. [PDF]

Microb Biotechnol
Xi Y, Liping Z, Yating X, Yang X, Jian C, Caiyun C, Shuwen L, Zian Z, Xiaojian Y, Shuwen H, Wei W.   +10 more
europepmc   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

Bacteriophage research in India and its implications for human health: A scoping review. [PDF]

Indian J Med Res
Das S, Mondal S, Hossain M, Asif M, Sen S, Mondal P, Kumar Chakrabarti A, Saha I, Tripathi SK, Das S, Pati S.   +10 more
europepmc   +1 more source

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source