Results 111 to 120 of about 13,845,628 (330)

Comparative analysis of salmonella typhi by rRNA gene restriction and phage typing

open access: yes, 2000
Phage typing and ribotyping were used to analyze 19 isolates of Salmonella typhi from sporadic cases and two outbreaks of typhoid fever in Malaysia in 1987 and 1990.
Thong, Kwai Lin, Pang, T., Altwegg, M.
core  

Role of genomic typing in taxonomy, evolutionary genetics, and microbial epidemiology. [PDF]

open access: yes, 2001
Currently, genetic typing of microorganisms is widely used in several major fields of microbiological research. Taxonomy, research aimed at elucidation of evolutionary dynamics or phylogenetic relationships, population ...
Struelens, M.   +18 more
core   +1 more source

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

open access: yesAdvanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu   +3 more
wiley   +1 more source

Development of an Assay for the Identification of Receptor Binding Proteins from Bacteriophages

open access: yesViruses, 2016
Recently, a large number of new technologies have been developed that exploit the unique properties of bacteriophage receptor binding proteins (RBPs).
David J. Simpson   +2 more
doaj   +1 more source

Bacteriophage Typing of Coagulase-Negative Staphylococci Isolated from Bovine Milk

open access: yes, 1981
The purpose of the present study is to determine whether the phages of the N.C.T.C. phage-set and Davidson's phage-set could be utilized in typing 417 coagulase-negative staphylococci from bovine milk and to device a new phage-set that would yield higher
BABA, Eiichiro   +2 more
core  

Engineered Transformer Base Editor with Enhanced Editing Efficiency

open access: yesAdvanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen   +5 more
wiley   +1 more source

Characterization of Salmonella Enteritidis isolated from foods and patients in northern Morocco

open access: yesJournal of Infection in Developing Countries, 2009
Objectives: This study aimed to investigate Salmonella Enteritidis strains isolated from human and food sources in the north of Morocco by means of phenotypic and genotypic methods.
Sanae Ammari   +5 more
doaj   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

open access: yesAdvanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi   +16 more
wiley   +1 more source

Staphylococcus aureus isolated from poultry in Australia. I. Phage typing and cultural characteristics

open access: yes
The phage typing and cultural characteristics of 574 strains of S. aureus of poultry origin in Australia were examined. With the avian phage set of Shimizu (1979) it was possible to type 74.2% of strains.

core   +1 more source

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

open access: yesAdvanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko   +5 more
wiley   +1 more source

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