Results 221 to 230 of about 41,388 (353)

Cas12Fold Accurately Predicts Cas12 Nuclease Structures to Enable Structure‐based Genome‐editing Engineering

open access: yesSmall Structures, EarlyView.
Cas12Fold, a deep‐learning framework tailored to Cas12 nucleases, uses evolutionary signals and iterative structure‐based alignment to resolve conformational complexity. This method outperforms general models in predicting key domains and states, accurately modeling enzymes such as Casλ.
Feng Xu   +12 more
wiley   +1 more source

Primary Isolation Strain Determines Both Phage Type and Receptors Recognised by Campylobacter jejuni Bacteriophages

open access: gold, 2015
Martine C. Holst Sørensen   +8 more
openalex   +2 more sources

Protein binding assessment of immobilized nanobody using interferometric nanoporous platform

open access: yesVIEW, EarlyView.
Nanoporous anodic alumina photonic chip technology is combined with tailor‐engineered “nanobodies”—recombinant variable domains of heavy‐chain‐only antibodies—to achieve high affinity binding to human serum albumin. Abstract Protein sensors are key tools for infectious disease diagnosis and monitoring.
Cheryl Suwen Law   +6 more
wiley   +1 more source

Genetic engineering for SIT application: a fruit fly‐focused review

open access: yesInsect Science, EarlyView.
Abstract Sterile insect technique (SIT) has become a key component of efficient pest control. Fruit fly pests from the Drosophilidae and Tephritidae families pose a substantial and overwhelmingly increasing threat to the agricultural industry, aggravated by climate change and globalization among other contributors.
Serafima Davydova   +2 more
wiley   +1 more source

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