Human Gut Bacteriophageome: Insights Into Drug Resistance Mechanisms in Tuberculosis [PDF]
Interdisciplinary Perspectives on Infectious DiseasesTuberculosis (TB), caused by Mycobacterium tuberculosis, remains a major global health burden. The emergence of drug-resistant strains presents a critical challenge in TB management.
Erfaneh Jafari +4 more
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Findings and methodologies in oral phageome research: a systematic review [PDF]
Journal of Oral MicrobiologyBackground The oral microbiome serves as both an indicator and a mediator of oral health. Evidence indicates that bacteriophages (phages) are widely present in the oral microbiome and exhibit diverse classifications and interactions with human cells and ...
Xin Chen +3 more
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The human phageome: niche-specific distribution of bacteriophages and their clinical implications [PDF]
Applied and Environmental MicrobiologyBacteriophages (phages) play a crucial role in shaping the composition and diversity of the human microbiome across various body niches. Recent advancements in high-throughput sequencing technologies have enabled comprehensive analysis of the human ...
Izabela Rybicka, Zuzanna Kaźmierczak
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Engrafting gut bacteriophages have potential to modulate microbial metabolism in fecal microbiota transplantation [PDF]
MicrobiomeBackground Fecal microbiota transplantation (FMT) is widely used to treat severe infections and investigated for the treatment of complex diseases. The therapeutic efficacy of FMT is related to the successful engraftment of bacteriophages from healthy ...
Shuai Ji +6 more
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The enteric DNA virome differs in infants at risk for atopic disease [PDF]
Gut MicrobesAtopic disease prevalence, including atopic dermatitis, food allergy, asthma, and allergic rhinitis, has risen dramatically in industrialized countries. Traditional, single family farming lifestyles protect against atopic disease, but the mechanisms are ...
Tyrus J. Perdue +7 more
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Metagenomic Analysis of the Gastrointestinal Phageome and Incorporated Dysbiosis in Children with Persistent Diarrhea of Unknown Etiology in Vietnam [PDF]
PathogensPersistent diarrhea of unknown etiology in children under 2 years of age is a common problem and poses a major challenge for the health sector. However, knowledge of the composition and dysbiosis of the intestinal phageome, phage-associated bacteriome in
Trong Khoa Dao +8 more
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Fecal microbiota transplantation alters gut phage communities in a clinical trial for obesity [PDF]
MicrobiomeBackground Fecal microbiota transplantation (FMT) is a therapeutic intervention used to treat diseases associated with the gut microbiome. In the human gut microbiome, phages have been implicated in influencing human health, with successful engraftment ...
Michele Zuppi +7 more
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Gut microbial and functional signatures in breast cancer: an integrated metagenomic and machine learning approach to non-invasive detection [PDF]
Frontiers in MicrobiologyIntroductionBreast cancer is associated with significant restructuring of the gut ecosystem. Gut microbial composition and function may influence cancer development and progression through immune modulation, metabolic regulation, and inflammation-related
Yalin Li +23 more
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Gut phageome in Mexican Americans: a population at high risk for metabolic dysfunction-associated steatotic liver disease and diabetes [PDF]
mSystemsMexican Americans are disproportionally affected by metabolic dysfunction-associated steatotic liver disease (MASLD), which often co-occurs with diabetes.
Suet-Ying Kwan +7 more
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Gut phages and their interactions with bacterial and mammalian hosts [PDF]
Journal of BacteriologyThe mammalian gut microbiome is a dense and diverse community of microorganisms that reside in the distal gastrointestinal tract. In recent decades, the bacterial members of the gut microbiome have been the subject of intense research.
Marshall Godsil +3 more
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